Evidence map›Paper›PMID 40595436›Full record

ArticleScientific reports2025

Genetic variation associated with increased lambda-cyhalothrin resistance in Spodoptera frugiperda (Lepidoptera: Noctuidae) in West Africa.

Eric Tossou, Ghislain T Tepa-Yotto, Georg Goergen, Genevieve M Tchigossou, Magellan Tchouakui, Daniel Nguiffo Nguete, Laouali Amadou, Moussa Noussourou, Aimé H Bokonon-Ganta, Charles Wondji and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cytochrome P450 GenesInsects · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eric TossouAgroecohealth Unit , International Institute of Tropical Agriculture (IITA) , 08 P.O. Tri-Postal, Box 0932, Cotonou, Benin. eric.tossou82@gmail.com.
Ghislain T Tepa-YottoBiorisk Management Facility (BIMAF), International Institute of Tropical Agriculture (IITA-Benin), 08 P.O. Tri-Postal, Box 0932, Cotonou, Benin.
Georg GoergenBiorisk Management Facility (BIMAF), International Institute of Tropical Agriculture (IITA-Benin), 08 P.O. Tri-Postal, Box 0932, Cotonou, Benin.
Genevieve M TchigossouAgroecohealth Unit , International Institute of Tropical Agriculture (IITA) , 08 P.O. Tri-Postal, Box 0932, Cotonou, Benin.
Magellan TchouakuiCentre for Research in Infectious Diseases (CRID), P.O. BOX 13591, Yaoundé, Cameroon.
Daniel Nguiffo NgueteCentre for Research in Infectious Diseases (CRID), P.O. BOX 13591, Yaoundé, Cameroon.
Laouali AmadouNational Institute of Agricultural Research (INRAN), P.O. BOX 240, Maradi, Niger.
Moussa NoussourouInstitute of Rural Economy (IER), P.O. BOX 438, Bamako, Mali.
Aimé H Bokonon-GantaLaboratory of Agricultural Entomology (LEAg), Faculty of Agronomic Sciences (FSA), University of Abomey-Calavi (UAC), P.O. Box 526, Abomey- Calavi, Benin.
Charles WondjiCentre for Research in Infectious Diseases (CRID), P.O. BOX 13591, Yaoundé, Cameroon.
Manuele TamòBiorisk Management Facility (BIMAF), International Institute of Tropical Agriculture (IITA-Benin), 08 P.O. Tri-Postal, Box 0932, Cotonou, Benin.
Rousseau DjouakaAgroecohealth Unit , International Institute of Tropical Agriculture (IITA) , 08 P.O. Tri-Postal, Box 0932, Cotonou, Benin. r.djouaka@cgiar.org.

Funding

German Federal Ministry for Economic Cooperation and Development (BMZ) 81235252 GARoyal Norwegian Embassy in Mali Grant MLI-17-0008Royal Norwegian Embassy in Niger Grant NER-17-0005Wellcome TrustWellcome Trust International Intermediate Fellowship 214201/Z/18/Z awarded to Rousseau Djouaka
6 · The paper itself

Abstract

The fall armyworm Spodoptera frugiperda (J.E. Smith) is a new serious destructive and widespread pest of corn which recently invaded subtropical regions worldwide. As this invasive species is spreading across the continent, it is vital to assess its susceptibility to currently used insecticides and establish the potential underlying resistance mechanism to better inform control programmes. In this study, we characterized the strains from eighteen fall armyworm populations from different countries in West Africa, established their susceptibility profiles to the main insecticides and genotyped the target site resistance alleles. The RFLP-PCR method showed that the majority of the population tested was a corn strain (72.5-100%) compared to the probable rice strain (0-27.5%). Tpi sequencing of the suspected rice strains revealed that almost all the samples analysed were from corn (> 97%). Additionally, the three insecticides tested, λ-cyhalothrin, chlorpyrifos and emamectin benzoate induced susceptible to moderate toxicity against this pest. Synergism tests performed to investigate the biochemical mechanism used by fall armyworm to breakdown λ-cyhalothrin indicated that metabolic enzymes (oxydases, esterase and the glutathion-S-transferase) play moderate roles in the resistance of λ-cyhalothrin observed in western Africa. Target mutation tests (qPCR) combined with previous synergetic tests showed that resistance to organophosphates and pyrethroids could be due to a biochemical mechanism + amino acid mutations (presence of the F290V mutation) or a biochemical mechanism (absence of the T929I mutation), respectively. The results of this study provide valuable information for supporting decisions related to sustainable fall armyworm control and applied resistance management.

Indexed as

Genetic VariationInsecticide ResistanceInsecticidesNitrilesPyrethrinsSpodopteraAfrica, WesternAnimalsZea mayscyhalothrinInsecticidesNitrilesPyrethrinsC-strainFall armywormInsecticide resistanceResistance managementR-strainTarget site mutationsWest Africa

Identifiers

PMID40595436
PMCPMC12216524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.