Evidence map›Paper›PMID 40595289›Full record

ArticleScientific reports2025

Abundance and transmission of antibiotic resistance and virulence genes through mobile genetic elements in integrated chicken and fish farming system.

S M Kador, Khondoker Tanjim Islam, Rafid Nahian Rubaiyat, Mohammad Imtiaj Uddin Bhuiyan, Tanay Chakrovarty, M Shaminur Rahman, Ovinu Kibria Islam, Md Tanvir Islam

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S M Kador *Department of Microbiology, Jashore University of Science and Technology, Jashore, Bangladesh.
Khondoker Tanjim Islam *Department of Microbiology, Jashore University of Science and Technology, Jashore, Bangladesh.
Rafid Nahian Rubaiyat *Department of Microbiology, Jashore University of Science and Technology, Jashore, Bangladesh.
Mohammad Imtiaj Uddin BhuiyanDepartment of Environmental Health Science, University of Georgia, Athens, GA, 30602, USA.
Tanay ChakrovartyDepartment of Microbiology, Jashore University of Science and Technology, Jashore, Bangladesh.
M Shaminur RahmanDepartment of Microbiology, Jashore University of Science and Technology, Jashore, Bangladesh.
Ovinu Kibria IslamDepartment of Microbiology, Jashore University of Science and Technology, Jashore, Bangladesh.
Md Tanvir IslamDepartment of Microbiology, Jashore University of Science and Technology, Jashore, Bangladesh. mt.islam@just.edu.bd.

Funding

Research Cell, Jashore University of Science and Technology 22-FoBST 05Special Research Grant, Ministry of Science and Technology, Bangladesh SRG-221252
6 · The paper itself

Abstract

Integrated chicken and fish farming systems, common in Bangladesh, present significant public health risks due to the spread of antimicrobial resistance genes (ARGs) and virulence factors (VFGs) through mobile genetic elements (MGEs). This study employs metagenomic sequencing to explore the diversity and abundance of ARGs, VFGs, and MGEs in various environmental samples from these farming systems. A total of 384 ARGs were detected, with tetracycline resistance genes such as tetM and tetX being the most abundant, alongside macrolide-lincosamide-streptogramin and aminoglycoside resistance genes. Droppings harbored the highest proportion of ARGs (62.2%), whereas sediment served as a reservoir for multi-metal resistance genes. Virulence factors associated with immune modulation, such as pvdL and tssH, and biofilm formation genes like algC were particularly prevalent in sediment and droppings. Among MGEs, plasmids and transposons like Tn6072 and Tn4001 were the most abundant, playing a critical role in horizontal gene transfer. Bacterial genera including Bacteroides, Clostridium, and Escherichia were strongly associated with MGEs, indicating their role in the dissemination of resistance and virulence traits. Statistical analyses revealed significant differences in the abundance of ARGs, VFGs, and MGEs across sample types, with sediment and droppings identified as hotspots for gene exchange. These findings underscore the urgent need for improved antibiotic stewardship and waste management practices to limit the spread of antimicrobial resistance and pathogenic bacteria within integrated farming environments.

Indexed as

BacteriaChickensDrug Resistance, BacterialDrug Resistance, MicrobialInterspersed Repetitive SequencesVirulence FactorsAnimalsAnti-Bacterial AgentsAquacultureBangladeshFishesGene Transfer, HorizontalVirulenceAnti-Bacterial AgentsVirulence FactorsAntimicrobial resistance genesHorizontal gene transferIntegrated farming systemsMobile genetic elementsVirulence factors

Identifiers

PMID40595289
PMCPMC12217527

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