Evidence map›Paper›PMID 40595159›Full record

ArticleScientific reports2025

Histone modification changes upon exposure of human lung adenocarcinoma cells to nanoparticles.

Xiaoxu Zhao, Liping Zhao, Hui Lin, Xiumei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoxu ZhaoFujian Provincial Key Laboratory of Ecology-Toxicological Effects & Control for Emerging Contaminants, Putian University, Putia, Fujian, China. zhaoxiaoxu0711@126.com.
Liping ZhaoCollege of Environmental and Biological Engineering, Putian University, Putian, Fujian, China.
Hui LinCollege of Environmental and Biological Engineering, Putian University, Putian, Fujian, China.
Xiumei WangCollege of Environmental and Biological Engineering, Putian University, Putian, Fujian, China. wxm890626@163.com.

Funding

Fujian Provincial Department of Science and Technology 2021J011105Fujian Provincial Department of Science and Technology 2024J01879National College Students' Innovation and Entrepreneurship Training Program Project 202411498002XNational Natural Science Foundation of China 31801462Putian University 2024035
6 · The paper itself

Abstract

The increasing use of nanoparticles in numerous applications has led to growing concern about their potential toxicological properties. However, the role of epigenetic alterations in toxicity due to nanoparticles remains relatively unexplored. In this study, we examined the effects of ten kinds of nanoparticles on histone modification. We observed that Al

Indexed as

Adenocarcinoma of LungHistonesLung NeoplasmsMetal NanoparticlesNanoparticlesA549 CellsAcetylationCell Line, TumorCopperHumansMethylationPhosphorylationZinc OxideCopperHistonesZinc OxideEpigeneticHistone modificationIntracellular accumulationIon releaseNanoparticles

Identifiers

PMID40595159
PMCPMC12217981

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.