Evidence map›Paper›PMID 40595087›Full record

Trial reportScientific reports2025

Anxiety, depression, quality of life and the mediating role of psychological flexibility: A study on Spanish cancer patients.

Francisco García-Torres, Margarita García-Carmona, Ángel Gómez-Solís, Francisco Jurado-González, Marcin Jablonski, María José Jaén-Moreno, Enrique Aranda

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05126823 (Efficacy of a Combined Acceptance and Commitment Intervention to Improve Psychological Flexibility and Associated Symptoms in Cancer Patients), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05126823 naactive not recruitingnot on this map

Efficacy of a Combined Acceptance and Commitment Intervention to Improve Psychological Flexibility and Associated Symptoms in Cancer Patients: a Randomized Controlled Clinical Trial

TypeinterventionalSponsorFrancisco Garcia TorresRan2022 to 2026Enrolled120ConditionsCancerArmsAcceptance and commitment therapy + app, Acceptance and commitment therapy
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francisco García-TorresDepartment of Psychology, Faculty of Educational Sciences and Psychology, University of Cordoba, San Alberto Magno Av, 14071, Cordoba, Spain. z12gatof@uco.es.
Margarita García-CarmonaDepartment of Psychology, Faculty of Educational Sciences and Psychology, University of Cordoba, San Alberto Magno Av, 14071, Cordoba, Spain.
Ángel Gómez-SolísReina Sofía University Hospital of Cordoba, Cordoba, Spain.
Francisco Jurado-GonzálezDepartment of Psychology, Faculty of Educational Sciences and Psychology, University of Cordoba, San Alberto Magno Av, 14071, Cordoba, Spain.
Marcin JablonskiJan Kochanowski University in Kielce: Uniwersytet Jana Kochanowskiego w, Kielcach, Poland.
María José Jaén-MorenoDepartment of Social Health Sciences, Radiology and Physical Medicine, University of Cordoba, Cordoba, Spain.
Enrique ArandaMedical Oncology Department, Reina Sofía University Hospital, Córdoba, Spain.

Funding

Consejería de Economía, Conocimiento, Empresas y Universidad of the Junta de Andalucía (Spain) P20_00485European Regional Development Fund P20_00485
6 · The paper itself

Abstract

Anxiety, depression and psychological flexibility appear to be correlated with quality of life in cancer patients. However, the mediating role of psychological flexibility between emotional distress and quality of life are unclear. The aim of the study was to investigate the mediating role of psychological flexibility in the relationships between anxiety, depression, and quality of life in cancer patients undergoing treatment. A hundred and nineteen cancer patients participated in the study by completing the Hospital Anxiety and Depression Scale, the Action and Acceptance Questionnaire II, and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire, version 3. Anxiety and depression correlated with psychological flexibility and quality of life. Psychological flexibility correlated with the quality of life scales but not with the diarrhoea and constipation. Mediation analysis showed that depression and anxiety indirectly influenced cognitive and social function through psychological flexibility. Depression indirectly influenced emotional functioning, dyspnoea and insomnia. The results obtained suggest that psychological flexibility may affect the relationship between emotional distress and different aspects of quality of life for cancer patients.Trial registration This research has been registered in www.ClinicalTrials.gov , identifier [NCT05126823] in 19/11/2021.

Indexed as

AnxietyDepressionNeoplasmsQuality of LifeAdultAgedFemaleHumansMaleMiddle AgedSpainSurveys and QuestionnairesAnxietyCancer patientsDepressionPsychological flexibilityQuality of lifeSpain

Identifiers

PMID40595087
PMCPMC12215487

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.