Evidence map›Paper›PMID 40595079›Full record

ArticleScientific reports2025

Fabrication of biodegradable nanocomposite scaffolds with hydroxyapatite, magnetic clay, and graphene oxide for bone tissue engineering.

Akram Babakhani, Seyed Jamaleddin Peighambardoust, Maryam Ghahremani-Nasab, Naeimeh Sadat Peighambardoust

Abstract read
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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Akram BabakhaniFaculty of Chemical and Petroleum Engineering, University of Tabriz, Tabriz, 5166616471, Iran.
Seyed Jamaleddin PeighambardoustFaculty of Chemical and Petroleum Engineering, University of Tabriz, Tabriz, 5166616471, Iran. j.peighambardoust@tabrizu.ac.ir.
Maryam Ghahremani-NasabStem Cell and Regenerative Medicine Innovation Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Naeimeh Sadat PeighambardoustKoç University Boron and Advanced Materials Application and Research Center (KUBAM), 34450, Sariyer, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone tissue engineering offers an alternative approach to producing scaffolds using biodegradable materials. The extracellular matrix of bone tissue comprises collagen and hydroxyapatite so that regenerated scaffolds can be a combination of polymeric materials and hydroxyapatite. Additives are also used to improve the properties and bring the properties of the regenerated scaffold closer to bone tissue. This study focuses on developing nanocomposite scaffolds composed of natural polymers carboxymethyl cellulose (CMC) and alginate (Alg), combined with the synthetic polymer polyvinyl alcohol (PVA) as the polymer matrix. The mechanical properties of these biopolymers were enhanced using magnetic clay nanoparticles modified with graphene oxide (CGF) and natural hydroxyapatite (HAp). Modified clay was synthesized by adding graphene oxide (via the modified Hummer's method), clay, and Fe

Indexed as

Bone and BonesClayDurapatiteGraphiteNanocompositesTissue EngineeringTissue ScaffoldsAlginatesBiocompatible MaterialsCarboxymethylcellulose SodiumHumansPolyvinyl AlcoholPorosityAlginatesBiocompatible MaterialsCarboxymethylcellulose SodiumClayDurapatitegraphene oxideGraphitePolyvinyl AlcoholBone tissue engineeringGraphene oxideHydroxyapatiteMagnetic nanoclayNanocomposite scaffold

Identifiers

PMID40595079
PMCPMC12216499

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.