Evidence map›Paper›PMID 40595047›Full record

ArticleScientific reports2025

Identifying and characterizing suicide decedent subtypes using deep embedded clustering.

Anas Belouali, Christopher Kitchen, Ayah Zirikly, Paul Nestadt, Holly C Wilcox, Hadi Kharrazi

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Anas BeloualiDivision of General Internal Medicine, Biomedical Informatics and Data Science (BIDS), Johns Hopkins School of Medicine, 2024 East Monument St. S 1-200, Baltimore, MD, 21205, USA. abeloua1@jhu.edu.
Christopher KitchenDepartment of Health Policy and Management, Center for Population Health Information Technology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Ayah ZiriklyCenter for Language and Speech Processing, Johns Hopkins Whiting School of Engineering, Baltimore, MD, USA.
Paul NestadtDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Holly C WilcoxDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Hadi KharraziDivision of General Internal Medicine, Biomedical Informatics and Data Science (BIDS), Johns Hopkins School of Medicine, 2024 East Monument St. S 1-200, Baltimore, MD, 21205, USA.

Funding

Advancing Maryland's Statewide Suicide Data Warehouse to Improve Individual and Population-level Mortality Prediction and PreventionR01MH124724 · NIMH · JOHNS HOPKINS UNIVERSITY · PI KHARRAZI, HADI · 2020 to 2023
$3.2M
Johns Hopkins Training Program in Biomedical Informatics and Data ScienceT15LM013979 · NLM · JOHNS HOPKINS UNIVERSITY · PI CHRISTOPHER G CHUTE, Hadi Kharrazi · 2022 to 2026
$2.2M
Harmonizing Multiple Data Sources And Psychological Autopsy To Characterize Suicides Among Opioid-Related DeathsK23DA055693 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Paul Sasha Nestadt · 2022 to 2026
$985k
NIDA NIH HHS K23 DA055693NIMH NIH HHS R01 MH124724NLM NIH HHS T15 LM013979US National Institute of Mental Health R01MH124724-01US National Library of Medicine T15LM013979-03
6 · The paper itself

Abstract

Subtypes of suicide decedents have not been studied at a population level using linked clinical and public health surveillance records. Identifying suicide subtypes can help facilitate the development and deployment of population-level prevention strategies. This retrospective study uses the Maryland Suicide Data Warehouse (MSDW). The analyses included 848 individuals who died by suicide as well as 4,161 individuals who died by accident in the state of Maryland between January 1st, 2016, and December 31st, 2019. These individuals had electronic health records from Johns Hopkins Medical Institutes and statewide hospital discharge data. We employed deep embedded clustering and evaluated its performance against traditional clustering approaches. We evaluated different numbers of clusters (k = 2 to 10) and assessed clustering performance using stability metrics, achieving a cross-validated prediction strength of 0.94. We then performed cluster characterization and assessed cluster stability up to 1 year before suicide death. We identified four distinct suicide profiles. Profile 1 (23.2% of suicide cases) included older individuals with high comorbid conditions. Profile 2 (19.2%) was characterized by psychiatric illness, the highest healthcare utilization, and significant social needs. Profile 3 (25.4%) consisted of younger individuals with psychiatric illness, no recorded social needs, and the highest percentage of Medicaid patients. Profile 4 (32.2%) included less clinically engaged individuals with the fewest healthcare visits. Our findings show the effective use of clustering methods to identify meaningful and stable suicide decedent profiles, revealing significant demographic and clinical differences. The identified subtypes can inform population-level suicide prevention strategies.

Indexed as

SuicideAdolescentAdultAgedCluster AnalysisElectronic Health RecordsFemaleHumansMaleMarylandMental DisordersMiddle AgedRetrospective StudiesYoung Adult

Identifiers

PMID40595047
PMCPMC12219903

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.