Evidence map›Paper›PMID 40595016›Full record

ArticleNature aging2025

Association of midlife hearing impairment and hearing aid use with incident dementia: analysis of two UK-based longitudinal cohort studies.

Marcos D Machado-Fragua, Aurore Fayosse, Julien Dumurgier, Mika Kivimaki, Céline Ben Hassen, Gill Livingston, Claire Paquet, Séverine Sabia, Archana Singh-Manoux

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcos D Machado-FraguaUniversité Paris Cité, Inserm U1153, Epidemiology of Ageing and Neurodegenerative Diseases, Paris, France.ORCID http://orcid.org/0000-0003-2646-1510
Aurore FayosseUniversité Paris Cité, Inserm U1153, Epidemiology of Ageing and Neurodegenerative Diseases, Paris, France.ORCID http://orcid.org/0000-0003-2646-9408
Julien DumurgierUniversité Paris Cité, Inserm U1153, Epidemiology of Ageing and Neurodegenerative Diseases, Paris, France.
Mika KivimakiFaculty of Brain Sciences, University College London, London, UK.ORCID http://orcid.org/0000-0002-4699-5627
Céline Ben HassenUniversité Paris Cité, Inserm U1153, Epidemiology of Ageing and Neurodegenerative Diseases, Paris, France.
Gill LivingstonFaculty of Brain Sciences, University College London, London, UK.ORCID http://orcid.org/0000-0001-6741-5516
Claire PaquetCognitive Neurology Center, Saint Louis-Lariboisiere-Fernand Widal Hospital, AP-HP, Université Paris Cité, Paris, France.
Séverine SabiaUniversité Paris Cité, Inserm U1153, Epidemiology of Ageing and Neurodegenerative Diseases, Paris, France. s.sabia@ucl.ac.uk.ORCID http://orcid.org/0000-0003-3109-9720
Archana Singh-ManouxUniversité Paris Cité, Inserm U1153, Epidemiology of Ageing and Neurodegenerative Diseases, Paris, France.ORCID http://orcid.org/0000-0002-1244-5037

Funding

Education, socioeconomic status and Aging: transitions from multimorbidity to functional limitations and mortalityR01AG056477 · NIA · UNIVERSITY COLLEGE LONDON · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2018 to 2022
$2.8M
Role of mid- and late-life risk factors in social inequalities in Alzheimer's Disease and Related DementiasRF1AG062553 · NIA · INSERM PARIS 5 · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2019 to 2019
$1.5M
Academy of Finland (Suomen Akatemia) 350426Agence Nationale de la Recherche (French National Research Agency) ANR-23-PAVH-0006.EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 101043884NIA NIH HHS R01 AG056477NIA NIH HHS RF1 AG062553Wellcome TrustWellcome Trust (Wellcome) 221854/Z/20/Z
6 · The paper itself

Abstract

The prevalence of hearing impairment and dementia increases with age but the nature of their association remains unclear. Using data from two large UK-based cohort studies, we examined the longitudinal association of 'midlife' hearing impairment and hearing aid use with incident dementia. We found modest associations and population attributable fractions for reported and measured 'midlife' hearing impairment, highlighting the need to consider age at measurement of risk factors in studies that target dementia prevention.

Indexed as

DementiaHearing AidsHearing LossAgedAged, 80 and overCohort StudiesFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedPrevalenceRisk FactorsUnited Kingdom

Identifiers

PMID40595016
PMCPMC12443597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.