Evidence map›Paper›PMID 40594948›Full record

ArticleScientific reports2025

Multidrug-resistant Klebsiella pneumoniae ST70 harboring bla

Sandryelle Merces Freire, Annelise Kyllar, Marina Côrtes, Thiago P G Chagas, Felipe Pinheiro, Renata F A Pereira, Fabio Aguiar-Alves, Bruno Penna

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sandryelle Merces FreireLaboratório de Cocos Gram Positivos do Instituto Biomédico, Universidade Federal Fluminense, Niterói, Brazil.
Annelise KyllarLaboratório de Cocos Gram Positivos do Instituto Biomédico, Universidade Federal Fluminense, Niterói, Brazil.
Marina CôrtesInstituto de Medicina Tropical da Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Thiago P G ChagasMolecular Epidemiology and Biotechnology Laboratory, Faculty of Pharmacy, Universidade Federal Fluminense, Niterói, Brazil.
Felipe PinheiroMolecular Epidemiology and Biotechnology Laboratory, Faculty of Pharmacy, Universidade Federal Fluminense, Niterói, Brazil.
Renata F A PereiraMolecular Epidemiology and Biotechnology Laboratory, Faculty of Pharmacy, Universidade Federal Fluminense, Niterói, Brazil.
Fabio Aguiar-AlvesPharmaceutical Sciences, Lloyd L. Gregory School of Pharmacy, Palm Beach Atlantic University, West Palm Beach, USA.
Bruno PennaLaboratório de Cocos Gram Positivos do Instituto Biomédico, Universidade Federal Fluminense, Niterói, Brazil. bpenna@id.uff.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 406057/2016-8Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E26/211.554/2019
6 · The paper itself

Abstract

The growing prevalence of antimicrobial resistance poses a global threat to human and animal health. In this study, we investigated the occurrence and genetic basis of antimicrobial resistance in a Magellanic Penguin (Spheniscus magellanicus) rescued off the coast of Rio de Janeiro, Brazil. The penguin presented a bacterial infection, identified as Klebsiella pneumoniae. Molecular analysis revealed the presence of several resistance genes, including those that confer resistance to carbapenems, beta-lactams, quinolones, and other classes of antibiotics. The bacterial strain belonged to Sequence Type 70 (ST70), a clone previously associated with human nosocomial infections. This study highlights the potential of migratory penguins as vectors of antimicrobial-resistant microorganisms, emphasizing the need for a One Health approach to address the complex interaction between environmental factors, animal health, and human well-being. The findings underscore the urgency of implementing strategies to mitigate the spread of multidrug-resistant bacteria in natural and urban environments.

Indexed as

beta-LactamasesDrug Resistance, Multiple, BacterialKlebsiella InfectionsKlebsiella pneumoniaeSpheniscidaeAnimalsAnti-Bacterial AgentsBrazilMicrobial Sensitivity TestsAnti-Bacterial Agentsbeta-lactamase NDM-1beta-Lactamases

Identifiers

PMID40594948
PMCPMC12216447

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.