Evidence map›Paper›PMID 40594921›Full record

ArticleScientific reports2025

Determination of bisphenol A in different types of soft drink samples by MSPE-GC/MS technique and contribution to risk assessment.

Samira Koti, Mir-Jamal Hosseini, Nabi Shariatifar, Adel Mirza Alizadeh, Fatemeh Izadpanah

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Samira KotiDepartment of Food Safety and Hygiene, Zanjan University of Medical Sciences, Zanjan, Iran.
Mir-Jamal HosseiniDepartment of Toxicology in the School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran. mhosseini@zums.ac.ir.
Nabi ShariatifarDepartment of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. nshariatifar@ut.ac.ir.
Adel Mirza AlizadehDepartment of Food Safety and Hygiene, Zanjan University of Medical Sciences, Zanjan, Iran.
Fatemeh IzadpanahFood and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA) is a chemical used in the production of plastics (polycarbonate) that can pose risks to human health. This research aimed to evaluate contents of BPA in soft drink samples (samples packaged in different containers and different volumes) by MSPEGC/MS (Magnetic Solid-Phase Extraction-Gas Chromatography/Mass Spectrometry) technique. Moreover, health risks of human were assessed for Iranian consumers by MCS method. Our results revealed, the average level of BPA in all samples was 1.83 ± 1.16 ppb (ranging from 0.45 to 5.10 ppb). BPA levels differed significantly among the samples depending on the type of packaging and pH level (P < 0.05). Also, the highest and lowest average levels of BPA in different soft drinks of different flavours/tastes were in cola soft drink samples (2.53 ppb) and energy drink samples (0.85 ppb), respectively. Furthermore, the highest and lowest average levels of BPA in soft drinks with different volumes were observed in 1500 cc soft drink samples (2.87 ppb) and 500 mL soft drink samples (0.9 ppb), respectively. The results of the MCS (Monte Carlo Simulation) indicated the 95th percentile for the THQ (Target Hazard Quotient) of BPA in soft drink samples was 9.61E + 1 for adults and 1.37E + 2 for children (6 years) (THQ > 1). Overall, these results imply that exposure to BPA could represent a potential health risk for individuals who frequently consume soft drinks packaged in PET (Polyethylene Terephthalate) or cans, especially for children.

Indexed as

Benzhydryl CompoundsCarbonated BeveragesFood ContaminationGas Chromatography-Mass SpectrometryPhenolsAdultBisphenol A CompoundsFood PackagingHumansIranRisk AssessmentSolid Phase ExtractionBenzhydryl Compoundsbisphenol ABisphenol A CompoundsPhenolsBisphenol AEnergy drinkFood safetyMSPE-GC/MSRisk assessmentSoft drinks

Identifiers

PMID40594921
PMCPMC12219696

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