ArticleScientific reports2025
Antibacterial activity of a conventional hydrogel and a nanoparticle based hydrogel containing Satureja khuzestanica essential oil.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Current Knowledge of the GenusPharmaceuticals (Basel, Switzerland) · 2026Review
- Development of Nigella sativa essential oil loaded keratin/gelatin cryogel with antimicrobial and antioxidant properties for wound dressing.Scientific reports · 2026Article
- Biopolymer Hydrogel-Based Nanocomposites Functionalized with Natural Products for Wound Dressings: Translational Advances in Drug Design, Development, and Therapeutic Wound Care.Drug design, development and therapy · 2026Review
- Review
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Authors and funding
6 authors.
Funding
Abstract
Bacterial infections are a major global health concern due to increasing antibiotic resistance and high mortality rates. Medicinal plants, such as Satureja khuzestanica essential oil (EO), offer a promising natural alternative for combating resistant pathogens. The bioactive composition of S. khuzestanica EO was analyzed using gas chromatography-mass spectrometry (GC-MS). Alginate/CarboxyMethyl Cellulose (CMC) and alginate nanoparticle/CMC hydrogels incorporating EO were formulated. Rheological properties were evaluated, and encapsulation efficiency was confirmed using Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy (ATR-FTIR). The antibacterial efficacy of these formulations was assessed against Staphylococcus aureus and Pseudomonas aeruginosa. GC-MS identified carvacrol, thymol, gamma-terpinene, ortho-cymene, and limonene as the major bioactive compounds. Rheological analysis revealed that all formulations exhibited shear-thinning behavior, following the Carreau-Yasuda model. Notably, the alginate nanoparticle/CMC hydrogel containing EO (H-AlgNP/CMC-EO) demonstrated significantly enhanced antibacterial activity, achieving complete (100%) inhibition of S. aureus and P. aeruginosa growth, surpassing conventional hydrogels. The superior antimicrobial performance of H-AlgNP/CMC-EO highlights its potential as a novel therapeutic approach for combating bacterial infections, warranting further investigation in biomedical applications.
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Registered trials
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