Evidence map›Paper›PMID 40594858›Full record

ArticleScientific reports2025

Dbl2 interacts with helicases and an endonuclease to maintain the integrity of repetitive regions.

Anetta Bakosova, Lubos Cipak, Nina Mayerova, Kamil Krol, Zsigmond Benko, Alexandra Pitelova, Peter Kolesar, Dominika Piatrova, Maria Smondrkova, Anna Maresova and 11 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Anetta Bakosova *Institute of Animal Biochemistry and Genetics, Centre of Biosciences, Slovak Academy of Sciences, 840 05, Bratislava, Slovakia.
Lubos Cipak *Biomedical Research Center, Department of Genetics, Slovak Academy of Sciences, Dubravska Cesta 9, 845 05, Bratislava, Slovakia.
Nina Mayerova *Department of Genetics, Faculty of Natural Sciences, Comenius University in Bratislava, 841 04, Bratislava, Slovakia.
Kamil KrolInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106, Warsaw, Poland.
Zsigmond BenkoInstitute of Animal Biochemistry and Genetics, Centre of Biosciences, Slovak Academy of Sciences, 840 05, Bratislava, Slovakia.
Alexandra PitelovaInstitute of Animal Biochemistry and Genetics, Centre of Biosciences, Slovak Academy of Sciences, 840 05, Bratislava, Slovakia.
Peter KolesarFaculty of Science, National Centre for Biomolecular Research, Masaryk University, Kamenice 5, 625 00, Brno, Czechia.
Dominika PiatrovaInstitute of Animal Biochemistry and Genetics, Centre of Biosciences, Slovak Academy of Sciences, 840 05, Bratislava, Slovakia.
Maria SmondrkovaDepartment of Genetics, Faculty of Natural Sciences, Comenius University in Bratislava, 841 04, Bratislava, Slovakia.
Anna MaresovaDepartment of Cell Biology, Faculty of Science, Charles University, 128 00, Praha 2, Czechia.
Lucia MolnarovaDepartment of Genetics, Faculty of Natural Sciences, Comenius University in Bratislava, 841 04, Bratislava, Slovakia.
Ingrid CipakovaBiomedical Research Center, Department of Genetics, Slovak Academy of Sciences, Dubravska Cesta 9, 845 05, Bratislava, Slovakia.
Veronika AltmannovaFaculty of Science, National Centre for Biomolecular Research, Masaryk University, Kamenice 5, 625 00, Brno, Czechia.
Jana BellovaInstitute of Chemistry, Slovak Academy of Sciences, Dubravska Cesta 9, 845 38, Bratislava, Slovakia.
Peter BarathInstitute of Chemistry, Slovak Academy of Sciences, Dubravska Cesta 9, 845 38, Bratislava, Slovakia.
Martin PrevorovskyDepartment of Cell Biology, Faculty of Science, Charles University, 128 00, Praha 2, Czechia.
Jan PalecekFaculty of Science, National Centre for Biomolecular Research, Masaryk University, Kamenice 5, 625 00, Brno, Czechia.
Lumir KrejciFaculty of Science, National Centre for Biomolecular Research, Masaryk University, Kamenice 5, 625 00, Brno, Czechia.
Juraj GreganDepartment of Chromosome Biology, University of Vienna, Vienna Biocenter (VBC), Dr. Bohr-Gasse 9, 1030, Vienna, Austria.
Adrianna SkonecznaInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106, Warsaw, Poland.
Silvia Bagelova PolakovaInstitute of Animal Biochemistry and Genetics, Centre of Biosciences, Slovak Academy of Sciences, 840 05, Bratislava, Slovakia. silvia.bagelova@savba.sk.

Funding

DoktoGrant AP0171the Austrian Science Fund (FWF) grant P30516the Czech Science Foundation grant GA23-05284Sthe Grant Agency of Charles University GAUK 248120the Slovak Grant Agency VEGA 1/0340/23the Slovak Grant Agency VEGA 2/0021/22the Slovak Research and Development Agency APVV-20-0141the Slovak Research and Development Agency APVV-22-0294
6 · The paper itself

Abstract

Helicases and endonucleases play crucial roles in genome maintenance by unwinding or cleaving various forms of DNA and RNA structures in order to facilitate essential biological processes, such as DNA replication and recombination. Here, we identified fission yeast Dbl2 as a potential interactor of several complexes that exhibit either helicase or endonuclease activity, namely Fml1-MHF, SCF

Indexed as

DNA HelicasesEndonucleasesRepetitive Sequences, Nucleic AcidSchizosaccharomycesSchizosaccharomyces pombe ProteinsDNA-Binding ProteinsDNA DamageDNA, FungalDNA ReplicationProtein BindingDNA-Binding ProteinsDNA, FungalDNA HelicasesEndonucleasesSchizosaccharomyces pombe ProteinsDbl2DNA repairHelicasesHomologous recombinationSchizosaccharomyces pombe

Identifiers

PMID40594858
PMCPMC12217596

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.