Evidence map›Paper›PMID 40594726›Full record

ArticleScientific reports2025

Potentially toxic metals in umbilical cord blood as a biomarker for passive smoker women.

Nazila Moftian, Hossein Arfaeinia, Fereshteh Talebi, Farshid Soleimani, Sara Dadipoor, Vali Alipour, Nazanin Abdi, Nooshin Abbasi, Nastaran Taherpour, Mehdi Sharafi

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nazila Moftian *Department of Health Education and Health Promotion, Faculty of Health and Nutrition, Bushehr University of Medical Sciences, Bushehr, Iran.
Hossein Arfaeinia *Systems Environmental Health and Energy Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.
Fereshteh TalebiFaculty of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran.
Farshid SoleimaniTobacco and Health Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. f.soleimani@hums.ac.ir.
Sara DadipoorTobacco and Health Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Vali AlipourTobacco and Health Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Nazanin AbdiFertility and Infertility Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Nooshin AbbasiStudent Research and Technology Committee of Bushehr University of Medical Sciences, Bushehr, Iran.
Nastaran TaherpourClinical Research Development Center of Shariati Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Mehdi SharafiInfectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Funding

Hormozgan University of Medical Sciences 4020555
6 · The paper itself

Abstract

Maternal environmental tobacco smoke (ETS) exposure during pregnancy may threat the health of mothers and their newborns. The present study was performed to determine the potentially toxic metals (PTMs) in umbilical cord blood as a biomarker for passive smoker women, as well as their association with neonatal birth indicators. In total 128 mothers (exposed: 64 and non-exposed: 64) were selected as participants. A volume of 2 mL umbilical cord blood was sampled from each participant, and PTMs including As, Pb, Cr, Al, Co, Cd, Zn, Cu, Mn, Fe, Se and Ni levels were analyzed by ICP-MS. The mean concentration levels of all PTMs in exposed group was higher than non-exposed (As: 1.76, Al: 1.49, Pb: 2.57, Cd: 1.04, Cr: 1.15, Co: 1.10, Zn: 1.05, Cu: 3.41, Mn: 1.56, Fe: 1.22, Se: 1.69 and Ni: 1.03 times fold). There were statistically significant differences between the mean levels of all PTMs (except Ni and Zn) in exposed and non-exposed groups (p-value˂0.05). In exposed group, the mean of weight, height, head circumference and chest circumference of newborns were 3058.12 ± 139.23 g, 48.50 ± 0.97 cm, 34.82 ± 0.61 cm and 32.65 ± 0.20, respectively. These values in non-exposed group were 3270.48 ± 192.49 g, 50.47 ± 0.95 cm, 34.91 ± 0.60 cm and 33.14 ± 0.38 cm, respectively. Newborns of ETS exposed mothers had significantly lower weight, height, Apgar 1 min, and chest circumference at birth. With regards to the results of the present study, more comprehensive studies should be conducted in future to identify the markers of long-term exposure to tobacco smoke and tracking the biomarkers of tobacco smoke exposure in other biological matrices such as newborns blood, meconium, feces and urine.

Indexed as

BiomarkersFetal BloodMaternal ExposureMetalsMetals, HeavyTobacco Smoke PollutionAdultFemaleHumansInfant, NewbornPregnancyBiomarkersMetalsMetals, HeavyTobacco Smoke PollutionCord bloodMaternal exposureMetalsNewbornsPassive smokingTobacco

Identifiers

PMID40594726
PMCPMC12217748

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.