Evidence map›Paper›PMID 40594659›Full record

ArticleScientific reports2025

Comparative study of the effects of different iron sources on bioavailability and gastrointestinal tolerability in iron-deficient rats.

Roger Mariné-Casadó, Yaiza Tobajas, Anna Antolín, Teresa Negra, Alan Connolly, Juan María Alcaide-Hidalgo, Antoni Caimari

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roger Mariné-CasadóTechnological Unit of Nutrition and Health, Eurecat, Centre Tecnològic de Catalunya, 43204, Reus, Spain. roger.marine@eurecat.org.
Yaiza TobajasTechnological Unit of Nutrition and Health, Eurecat, Centre Tecnològic de Catalunya, 43204, Reus, Spain.
Anna AntolínTechnological Unit of Nutrition and Health, Eurecat, Centre Tecnològic de Catalunya, 43204, Reus, Spain.
Teresa NegraLubrizol Nutraceuticals, 08850, Gavà, Spain.
Alan ConnollyLubrizol Nutraceuticals, 08850, Gavà, Spain.
Juan María Alcaide-HidalgoTechnological Unit of Nutrition and Health, Eurecat, Centre Tecnològic de Catalunya, 43204, Reus, Spain.
Antoni CaimariBiotechnology Area, Eurecat, Centre Tecnològic de Catalunya, 43204, Reus, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron deficiency anaemia is a global health issue affecting millions of people. Though effective, conventional iron sources used for supplementation often cause gastrointestinal side effects. This preclinical study evaluated the efficacy and tolerability of three iron supplements-ferrous bisglycinate, LIPOFER™ microcapsules (Def-LFe1), and a commercially available microencapsulated iron pyrophosphate (Def-Fe2)-in reversing diet-induced iron deficiency in rats compared to FeSO

Indexed as

Anemia, Iron-DeficiencyFerrous CompoundsGastrointestinal TractIronAnimalsBiological AvailabilityDietary SupplementsDiphosphatesMaleRatsDiphosphatesferric pyrophosphateFerrous CompoundsIronFerrous sulfateGastrointestinal side effectsInflammationIron bioavailabilityIron supplementationLIPOFER™

Identifiers

PMID40594659
PMCPMC12217685

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.