Evidence map›Paper›PMID 40594636›Full record

ArticleScientific reports2025

Empathy and mental health distress in informal caregivers of dementia and stroke patients: a cross-sectional study.

Jing Mei, Yi He, Jia Li, Fang Chen, Shihua Pan, Yang Xu, Huimin Sun

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jing Mei *Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Yi He *Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Jia Li *Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Fang ChenDepartment of Neurology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Shihua PanDepartment of General Practice, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Yang XuDepartment of Neurology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Huimin SunDepartment of Neuropsychology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. huimin1968@163.com.

Funding

Medical Sci-Tech Innovation Platform of Zhongnan Hospital, Wuhan University PTXM2023029
6 · The paper itself

Abstract

Informal caregivers of patients with neurodegenerative diseases are confronted with significant psychological distress. However the role of empathy in their mental health distress remains understudied. This study addressed this gap by investigating the association between empathy and mental health outcomes with three groups (130 dementia caregivers, 130 stroke caregivers and 132 non-caregivers) through quantitative surveys. Measures included the Chinese Perceived Stress Scale (CPSS), Irritability, Depression, and Anxiety Scale (IDA), the Chinese Interpersonal Reactivity Index (IRI-C), and sociodemographic questionnaires. We found that dementia caregivers presented higher total empathy and depression scores than did stroke caregivers and non-caregivers. Stroke caregivers reported significantly greater perceived stress than did both groups. Among caregivers, cognitive empathy (IRI-C subscales) and positive affective empathy were inversely associated with the IDA and CPSS dimensions(e.g., depression, anxiety, irritability and perceived distress). Conversely, negative affective empathy was positively correlated with most psychological distress indicators. These findings highlight that cognitive empathy and positive affective empathy may serve as protective factors against mental health issues in informal caregivers, whereas negative affective empathy exacerbates psychological burden. Interventions targeting empathy enhancement (particularly cognitive components) could mitigate caregiver distress. Future research should explore causal mechanisms and test empathy-focused interventions in geriatric care settings.

Indexed as

CaregiversDementiaEmpathyMental HealthPsychological DistressStress, PsychologicalStrokeAdultAgedAged, 80 and overAnxietyCross-Sectional StudiesDepressionFemaleHumansMaleAnxietyDementiaDepressionEmpathyInformal caregiverStressStroke

Identifiers

PMID40594636
PMCPMC12215987

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.