ArticleScientific reports2025
Analysis of the effects of corneal and lens characteristics on peripheral defocus of the retina and its relationship with myopia.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Effect of combining peripheral defocus spectacle lens wear with 0.01% atropine.Annals of translational medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
This study investigated the effects of corneal and lens characteristics, including refractive power, thickness, and curvature, on peripheral defocus and their impact on different regions. A cross-sectional study was conducted involving 296 patients with myopia using data from the right eye. Peripheral retinal defocus was measured using a novel device, a multispectral refractive topographer, which can assess peripheral defocus. Retinal images were sequentially captured using single-wavelength monochromatic light at varying wavelengths to determine the refractive status of the fundus. Select relevant data at the corneal diameters of 4 mm, 6 mm, and 8 mm (superior, inferior, nasal and temporal). The refractive power of the superior cornea negatively correlated with peripheral defocus in inferior regions. Specifically, cornea refractive power at the 4 mm position below the cornea negatively correlated with peripheral defocus in inferior regions (r = -0.130, P < 0.05; r = -0.141, P < 0.05). Temporal corneal refractive power was negatively correlated with peripheral defocus in certain inferior regions. Nasal corneal refractive power negatively correlated with peripheral defocus in inferior regions and positively correlated with peripheral defocus in superior regions. Lens refractive power was positively correlated with peripheral defocus in superior regions and negatively correlated with peripheral defocus in inferior regions. Refractive media such as the cornea and lens are strongly associated with peripheral defocus in different regions. Among these, corneal refractive power exerts the most significant influence. Inferior peripheral defocus exhibits significant correlations with superior, temporal, and nasal corneal refractive powers. Temporal and inferior hyperopic peripheral defocus demonstrate a stronger association with myopia compared to other regions.
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Registered trials
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