Evidence map›Paper›PMID 40594364›Full record

ArticleScientific reports2025

Investigating the efficacy of bioactive compounds from selected plant extracts against Gibberella fujikuroi species complex associated with damping off disease in sweet corn.

Alyaa Abd Ali, Ayoob Obaid Alfalahi, Aalaa Khudhair Hassan, Ahlam Khalofah, Eilyn Mena, Abdelfattah A Dababat, Fouad Mokrini

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Essential Oils ofPathogens (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alyaa Abd AliDepartment of Plant Protection, College of Agriculture, University of Anbar, Anbar, Iraq.
Ayoob Obaid AlfalahiDepartment of Plant Protection, College of Agriculture, University of Anbar, Anbar, Iraq. ag.ayoob.obaid@uoanbar.edu.iq.
Aalaa Khudhair HassanDepartment of Plant Protection, College of Agricultural and Engineering Sciences, University of Baghdad, Baghdad, Iraq.
Ahlam KhalofahDepartment of Biology, College of Science, King Khalid University, Abha, Saudi Arabia.
Eilyn MenaInstituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.
Abdelfattah A DababatInternational Maize and Wheat Improvement Center (CIMMYT), Ankara, Turkey.
Fouad MokriniNematology Laboratory, Biotechnology Research Unit, Regional Center of Agricultural Research, INRA, Rabat, Morocco.

Funding

Deanship of Research and Graduate Studies,King Khalid University, Saudi Arabia RGP2/526/45
6 · The paper itself

Abstract

Fusarium genera are widespread disease-causing fungi that severely reduce plant productivity and yield quality, particularly in corn. In this study, we investigated the antifungal potential of selected plant extracts against damping-off disease-associated fungi in sweet corn (Zea mays L. saccharata). Fourteen Fusarium isolates were obtained from symptomatic sweet corn plants belonging to five different species, viz. F. fujikuroi, F. proliferatum, F. verticillioides, F. oxysporum, and F. acuminatum. Although all the isolated fungi were pathogenic, F. verticillioides (Fv-A), F. fujikuroi (Ff-A) and F. oxysporum (Fo-W2) were more aggressive showing higher values for infection (%) and infection severity (%) and negatively affected seed germination (%) and other growth variables. Phytochemical analysis for five wildly growing plant species namely; Eruca vesicaria L., Strigosella africana L., Chenopodium album L., Oxalis pes-caprae L. and Ducrosia ismaelis was conducted using GC-MS analysis. The most abundant bioactive compounds in the three selected extracts (E. vesicaria, O. pes-caprae L. and D. ismaelis) were 1-eicosanol, (Z)6,(Z)9-Pentadecadien-1-ol and n-Hexadecanoic acid, and Nonadecane, respectively. Oxacyclotricosan-2-one and D-Homoandrostane from E. vesicaria L.; Vitamin E and Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, methyl ester from O. pes-caprae L. and 7.beta.-(1-hydroxy-1-methylethyl), alpha-gurjunene from D. ismaelis showed extraordinary molecular docking and dynamic properties including high binding free energy, relatively low inhibition constant (pKi), ligand efficiency, and low torsional energy against three fungal enzymes, namely GH10 xylanase, Plant-type chitinase inhibitors, and Sterol 14-alpha Demethylase. Thus, these bioactive compounds can be listed as potential binders of these target proteins and could be used in designing new fungicides.

Indexed as

Antifungal AgentsGibberellaPlant DiseasesPlant ExtractsZea maysFusariumPhytochemicalsAntifungal AgentsPhytochemicalsPlant ExtractsAntifungal propertiesGibberella fujikuroiIn SilicoPhytoconstituentsSweet corn

Identifiers

PMID40594364
PMCPMC12218985

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.