ArticleScientific reports2025
Investigating biological sex as a moderator of the association of nature exposure with brain health: a cross-sectional UK biobank analysis.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In this cross-sectional analysis of the UK Biobank, we investigated whether biological sex moderates the association of residential nature exposure with brain volume or cognitive function. We included 11,448 cognitively healthy UK residents aged 37-73 years (98% White; 51% female). Residential nature exposure was estimated as the percentage of land classified as natural environment within 1000 m and 300 m buffers around each participant's home. Structural brain magnetic resonance imaging (MRI) outcomes included total grey matter volume, total white matter volume, and average hippocampal volume, all normalized for head size. Cognitive function was assessed with the Trail Making Test (B-A) and the Symbol Digit Substituton Test. In linear regression models, higher residential nature exposure at both buffer sizes was associated with greater grey matter volume (1000 m: β = 629 mm
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