Evidence map›Paper›PMID 40594215›Full record

ArticleScientific reports2025

Optimizing the early diagnosis of neurological disorders through the application of machine learning for predictive analytics in medical imaging.

Vijaya Bhaskar Sadu, Sathvik Bagam, Mohd Naved, Siva Krishna Reddy Andluru, Kamalakar Ramineni, Meshal Ghalib Alharbi, Sudhakar Sengan, Rahmaan Khadhar Moideen

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vijaya Bhaskar SaduDepartment of Mechanical Engineering, Jawaharlal Nehru Technological University, Kakinada, 533003, Andhra Pradesh, India.
Sathvik BagamSoftware Development Team Lead at Paycom, Master of Computer Science, Oklahoma Christian University, Edmond, Oklahoma, 73013, USA.
Mohd NavedDepartment of Business Analytics, Jaipuria Institute of Management, Noida, Uttar Pradesh, 201309, India.
Siva Krishna Reddy AndluruDepartment of Computer Science and Engineering, Koneru Lakshmaiah Education Foundation, Hyderabad, 500075, Telangana, India.
Kamalakar RamineniSchool of Engineering, Anurag University, Hyderabad, Telangana, 500088, India.
Meshal Ghalib AlharbiDepartment of Computer Science, College of Computer Engineering and Sciences, Prince Sattam Bin Abdulaziz University, Al-Kharj, 16278, Saudi Arabia.
Sudhakar SenganDepartment of Computer Science and Engineering, PSN College of Engineering and Technology, Tirunelveli, 627451, Tamil Nadu, India. sudhasengan@gmail.com.
Rahmaan Khadhar MoideenDepartment of Artificial Intelligence and Data Science, Mahendra Engineering College, Mallasamudram, Namakkal, Tamil Nadu, 637503, India. ksrahmaan2204@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early diagnosis of Neurological Disorders (ND) such as Alzheimer's disease (AD) and Brain Tumors (BT) can be highly challenging since these diseases cause minor changes in the brain's anatomy. Magnetic Resonance Imaging (MRI) is a vital tool for diagnosing and visualizing these ND; however, standard techniques contingent upon human analysis can be inaccurate, require a long-time, and detect early-stage symptoms necessary for effective treatment. Spatial Feature Extraction (FE) has been improved by Convolutional Neural Networks (CNN) and hybrid models, both of which are changes in Deep Learning (DL). However, these analysis methods frequently fail to accept temporal dynamics, which is significant for a complete test. The present investigation introduces the STGCN-ViT, a hybrid model that integrates CNN + Spatial-Temporal Graph Convolutional Networks (STGCN) + Vision Transformer (ViT) components to address these gaps. The model causes the reference to EfficientNet-B0 for FE in space, STGCN for FE in time, and ViT for FE using AM. By applying the Open Access Series of Imaging Studies (OASIS) and Harvard Medical School (HMS) benchmark datasets, the recommended approach proved effective in the investigations, with Group A attaining an accuracy of 93.56%, a precision of 94.41% and an Area under the Receiver Operating Characteristic Curve (AUC-ROC) score of 94.63%. Compared with standard and transformer-based models, the model attains better results for Group B, with an accuracy of 94.52%, precision of 95.03%, and AUC-ROC score of 95.24%. Those results support the model's use in real-time medical applications by providing proof of the probability of accurate but early-stage ND diagnosis.

Indexed as

Alzheimer DiseaseMachine LearningMagnetic Resonance ImagingNervous System DiseasesDeep LearningEarly DiagnosisHumansNeural Networks, ComputerROC CurveAUC-ROCDeep learningMagnetic resonance imagingNeurological disordersSpatial–temporal graph convolutional networksVision transformer

Identifiers

PMID40594215
PMCPMC12217182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.