Effects of vagal denervation on cerebral blood flow regulation immediately after the onset of ventricular pacing in anesthetized rats.

Kei Ishii, Hidehiko Komine, Takeyuki Oba

Abstract read

In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kei IshiiHuman Informatics and Interaction Research Institute, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8566, Japan. kei-ishii@aist.go.jp.ORCID http://orcid.org/0000-0002-9423-2923

Hidehiko KomineHuman Informatics and Interaction Research Institute, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8566, Japan.

Takeyuki ObaHuman Informatics and Interaction Research Institute, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8566, Japan.

Funding

Japan Society for the Promotion of Science 20K19473

6 · The paper itself

Abstract

Cerebral blood flow (CBF) appears to be selectively distributed in vital brain regions during rapid severe hypotension caused by tachyarrhythmia. To examine the effect of cardiopulmonary vagal afferent signals on region-specific CBF regulation, we compared CBF responses 1-4 s from the onset of ventricular pacing (at 550-850 beats/min) between vagotomized and sham-operated anesthetized male Wistar rats. Laser Doppler flowmetry was used to measure CBF in nine different brain regions from the cortex to the pons. The effects of vagotomy on cerebrovascular responsiveness to 5% CO

Indexed as

Cardiac Pacing, ArtificialCerebrovascular CirculationVagotomyVagus NerveAnesthesiaAnimalsBlood PressureHeart RateHeart VentriclesHypotensionLaser-Doppler FlowmetryMaleRatsRats, WistarCardiopulmonary afferentsCerebral blood flowVagotomyVentricular tachycardia

Identifiers

PMID40594180

DOI10.1038/s41598-025-05406-1

PMCPMC12215790

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.