Evidence map›Paper›PMID 40594030›Full record

ArticleScientific reports2025

Development and validation of the airway surgery enclosure for high-risk aerosol-generating airway procedures: a bench and clinical study.

Neil K Chadha, Jason Powell, Katharina Leitmeyer, Mark Felton, Alberto Baldelli, Michael Rooney, Fraser G L Parlane, Robert Purdy

Erratum issuedAbstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Neil K ChadhaDivision of Pediatric Otolaryngology-Head and Neck Surgery, BC Children's Hospital, University of British Columbia, 4480 Oak Street, Vancouver, BC, Canada. NChadha@cw.bc.ca.
Jason PowellDivision of Pediatric Otolaryngology-Head and Neck Surgery, BC Children's Hospital, University of British Columbia, 4480 Oak Street, Vancouver, BC, Canada.
Katharina LeitmeyerDivision of Pediatric Otolaryngology-Head & Neck Surgery, University Children's Hospital of Basel, Basel, Switzerland.
Mark FeltonDivision of Pediatric Otolaryngology-Head and Neck Surgery, BC Children's Hospital, University of British Columbia, 4480 Oak Street, Vancouver, BC, Canada.
Alberto BaldelliFaculty of Food and Land Systems, University of British Columbia, Vancouver, Canada.
Michael RooneyDepartment of Chemistry, The University of British Columbia, Vancouver, BC, Canada.
Fraser G L ParlaneDepartment of Chemistry, The University of British Columbia, Vancouver, BC, Canada.
Robert PurdyDepartment of Pediatric Anesthesia, BC Children's Hospital, University of British Columbia, Vancouver, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Procedures on the upper airway in patients with respiratory viruses are considered to carry the greatest risk of infection spread to operating room personnel through aerosolization. Appropriate personal protective equipment must be worn, but availability varies worldwide and resources may be limited. We describe the development, validation, and safe implementation of a reusable enclosure with an inexpensive, acrylic design, for use in high-risk airway procedures. Examples of common yet high-risk, aerosol-generating procedures performed with the Airway Surgery Enclosure (ASE) include laryngo-bronchoscopy, suspension laryngoscopy for removal of airway lesions, and rigid bronchoscopy including airway foreign body removal. The ASE demonstrated an 87-94% reduction in aerosolized particle concentration compared to ambient room levels. Bench testing validated the containment capability through laser-based particle imaging and air sampling, while clinical evaluations confirmed ergonomic feasibility and usability. While the ASE provides significant reductions in aerosol exposure, implementation challenges include integration with existing operating room workflows, material durability over repeated sterilization cycles, and cost considerations for widespread adoption. Further studies are needed to assess long-term clinical effectiveness and user adaptability.

Indexed as

Operating RoomsPersonal Protective EquipmentAerosolsBronchoscopyEquipment DesignHumansInfectious Disease Transmission, Patient-to-ProfessionalLaryngoscopyAerosolsAirborne virusesAirway enclosureCOVID-19LaryngoscopyProtective equipment

Identifiers

PMID40594030
PMCPMC12216345

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.