ArticleScientific reports2025
Urine pH is associated with the development of acute kidney injury in crush syndrome.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Value of Serum CK in Predicting Traumatic Rhabdomyolysis Induced Acute Kidney Injury: A Systematic Review and Meta-Analysis.Archives of academic emergency medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute kidney injury (AKI) is a critical complication in crush syndrome (CS). This retrospective study, performed from May 1st, 2019, to April 30th, 2024, analyzed 231 CS patients to identify AKI predictors. We compared urine pH, creatine kinase (CK), and serum creatinine on days 1, 3, 5, and 7 between AKI and non-AKI groups. AKI patients were older and had more severe trauma (p < 0.05). Urine pH progressively declined in the AKI group, remaining lower than non-AKI (except admission day), while CK and creatinine rose continuously (p < 0.05). Multivariable analysis identified urine pH on day 5 [odds ratio (OR) 0.301, p = 0.001], CK on day 1 (OR 1.000, p = 0.023) and Injury Severe Score (ISS) scores (OR 1.082, p = 0.008) as independent AKI predictors. The area under the ROC curve (AUC) for urine pH (day 5), CK (day 1) and ISS scores were 0.975, 0.838 and 0.761, respectively. The current study showed that urine pH persistently decreases in CS-related AKI, whereas CK increases. Urine pH on day 5, CK on day 1 and ISS scores independently predict AKI, highlighting potential ability of urine pH for early intervention and risk assessment in CS patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.