Evidence map›Paper›PMID 40593952›Full record

ArticleScientific reports2025

Correction of syndesmotic malreduction following fixation flexibilization.

Nacime Salomao Barbachan Mansur, Donald Hume, John Kwon, Kepler Alencar Mendes de Carvalho, Kevin Dibbern, Cesar de Cesar Netto

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Injuries of the tibiofibular syndesmosis].Unfallchirurgie (Heidelberg, Germany) · 2026
    Article
  2. [Clinical study on reduction of posterior malleolar fractures via modified Rammelt transfibular approach].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nacime Salomao Barbachan MansurDivision of Foot and Ankle Surgery, Department of Orthopaedic Surgery, Duke University Health System, Durham, USA. nacime.mansur@duke.edu.
Donald HumeParagon 28, Englewood, USA.
John KwonDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, USA.
Kepler Alencar Mendes de CarvalhoDepartment of Orthopaedics and Rehabilitation, Carver College of Medicine, University of Iowa, Iowa City, USA.
Kevin DibbernDepartment of Orthopaedics and Rehabilitation, Carver College of Medicine, University of Iowa, Iowa City, USA.
Cesar de Cesar NettoDivision of Foot and Ankle Surgery, Department of Orthopaedic Surgery, Duke University Health System, Durham, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prior studies showed the potential of a rigid fixation, such as a trans-syndesmotic screw, to produce tibiofibular malreduction. Flexible implants, although capable of allowing forgiveness, may not provide sufficient stability for all injury patterns. To assess the malreduction forgiveness of a two-phase syndesmotic device that is designed to transition from a rigid screw construct to a flexible suture-type. Cadaveric specimens were loaded in a frame under four conditions: native (control), syndesmotic instability (injured), malreduced with engaged syndesmotic device (malreduced), and post-disengagement (disengaged). The malreduction targets were 5 mm anterior displacement, 5 mm posterior displacement, 15° of rotation, and 140 N over-compressed. Fixation was performed with a single device 20 mm proximal to the ankle, manually disengaged to allow semi-constrained motion of the syndesmosis. Weightbearing Computed Tomography (WBCT) scans were obtained, and anatomic axes of the tibia and fibula extracted to calculate tibiofibular joint position with an established orthogonal system. A total of 42 specimens were included and allocated in the four groups. Anterior and posterior malreduction demonstrated 2.50 mm (SD: ±1.37 mm) and 5.04 mm (SD: ±2.23 mm) of average malreduction. The disengaged condition resulted in average recovery of 1.79 mm (95%CI: 0.72|2.85; p = 0.0034; 72% recovery) and 1.69 mm (95%CI: 0.09|3.28; p = 0.0006; 33% recovery) toward the control position, for anterior and posterior malreduction, respectively. Rotational malreduction demonstrated 2.44° (SD: ±2.09°) of average rotational malreduction, with 1.98° (95%CI: -0.13°|4.09°; p = 0.0707; 81%) of recovery. Over-compression specimens showed average medial translation of 0.89 mm (SD: ±1.10 mm), with 0.74 mm (95%CI: 0.05|1.51; p = 0.0128; 82%) of recovery when disengaged. The two-phase syndesmotic device was able to allow partial malreduction recovery in different scenarios after transitioning to the flexible state. The use of this implant might mitigate potential surgical tibiofibular malreductions while providing the mechanical and clinical advantages of both rigid and flexible devices. Level V. Controlled laboratory study.

Indexed as

Ankle InjuriesAnkle JointFracture Fixation, InternalJoint InstabilityBone ScrewsCadaverFemaleFibulaHumansMaleMiddle AgedTibiaWeight-Bearing

Identifiers

PMID40593952
PMCPMC12218112

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.