Evidence map›Paper›PMID 40593930›Full record

ArticleNPJ Parkinson's disease2025

Effects of two types of repetitive transcranial magnetic stimulation on brain network in Parkinson's disease.

Shuo Liu, Shuo Yang, Chen Wang, Jiarui Li, Lei Wang

Registry-linked trialAbstract read
In one paragraph

Article in NPJ Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07176091 (Clinical Efficacy of Intermittent Theta Burst Transcranial Magnetic Stimulation With Different Modes on Parkinson's Disease), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07176091 naenrolling by invitationnot on this map

Clinical Efficacy of Intermittent Theta Burst Transcranial Magnetic Stimulation With Different Modes on Parkinson's Disease

TypeinterventionalSponsorSecond Affiliated Hospital of Soochow UniversityRan2025 to 2027Enrolled90ConditionsParkinsonism, Transcranial Magnetic Stimilation, Intermittent Theta Burst Stimulation, Primary Motor CortexArmsHigh-dose iTBS treatment group, Low-dose iTBS treatment group, Sham stimulation group
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Differential neural responses to rhythmic and patterned TMS protocols: Insights from EEG spectral analysis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuo LiuSchool of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin, 300130, China.
Shuo YangSchool of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin, 300130, China. sureyang@126.com.
Chen WangSchool of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin, 300130, China.
Jiarui LiSchool of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin, 300130, China.
Lei WangSchool of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin, 300130, China.

Funding

Hebei Provincial Key Research Projects 21372002DNational Natural Science Foundation of China 52320105008
6 · The paper itself

Abstract

Intermittent theta burst stimulation (iTBS) may have higher efficiency and stronger excitatory effects compared to conventional high-frequency repetitive transcranial magnetic stimulation (HF-rTMS). To evaluate the therapeutic effects of the two modalities, we compared the differences in spatiotemporal variability of electroencephalography (EEG) microstate-based brain networks between 51 PD patients and 21 healthy controls. The 51 PD patients were randomly assigned to either iTBS or 10Hz-rTMS groups to compare pre- and post-treatment clinical assessment results and spatiotemporal variability changes. Baseline measurements showed significant differences in spatiotemporal variability between PD patients and healthy controls, with certain brain regions demonstrating significant correlations between spatiotemporal variability and clinical assessment results. Both treatment groups exhibited significant improvements in all clinical outcomes compared to baseline. The iTBS group showed post-treatment changes involving more brain regions in spatiotemporal variability. This study demonstrates that compared to 10Hz-rTMS, iTBS can reduce treatment time while providing superior improvement in functional brain connectivity for PD patients.

Identifiers

PMID40593930
PMCPMC12218465

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.