Evidence map›Paper›PMID 40593870›Full record

ArticleScientific data2025

Whole genome sequences of 297 Duolang sheep for litter size.

Chao Fang, Tom Druet, Hang Cao, Wujun Liu, Qiuming Chen, Frederic Farnir

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Multiomics Analysis across the Life Cycle Identifies ZnJournal of agricultural and food chemistry · 2026
    Article
  4. Functional characterization of HMG_9 and CMicrobial cell factories · 2026
    Article
  5. Article
  6. Review
  7. Rapid Identification of the SNP Mutation in theAnimals : an open access journal from MDPI · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chao FangFaculte de Medecine Veterinaire, Universite de Liege, Quartier Vallee 2, Avenue de Cureghem 6 (B43), 4000, Liege, Belgium.
Tom DruetFaculte de Medecine Veterinaire, Universite de Liege, Quartier Vallee 2, Avenue de Cureghem 6 (B43), 4000, Liege, Belgium.
Hang CaoCollege of Animal Science, Xinjiang Agricultural University, Urumqi, 830052, China.
Wujun LiuCollege of Animal Science, Xinjiang Agricultural University, Urumqi, 830052, China.
Qiuming ChenFaculte de Medecine Veterinaire, Universite de Liege, Quartier Vallee 2, Avenue de Cureghem 6 (B43), 4000, Liege, Belgium. cqm19860612@126.com.ORCID 0000-0002-2334-176X
Frederic FarnirFaculte de Medecine Veterinaire, Universite de Liege, Quartier Vallee 2, Avenue de Cureghem 6 (B43), 4000, Liege, Belgium. f.farnir@uliege.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Litter size is a critical economic trait in the sheep industry. Like many other breeds, Duolang sheep typically produce one lamb per ewe per lambing. To date, genetic studies of this trait in that breed have largely relied on candidate gene approaches. To expand the genomic resources for this breed, we sequenced 297 genomes, generating approximately 10.52 trillion bases with an average coverage of 13.35X. High-quality alignments with a mapping rate exceeding 99% enabled the identification of 43,968,128 SNPs and 6,504,047 InDels. This dataset provides a valuable resource for identifying genetic variants associated with litter size through genome-wide association studies (GWAS) and lays the foundation for future genetic improvement efforts through genomic selection in Duolang sheep. Beyond trait mapping, the dataset also supports broader applications, including analyses of genetic diversity, phylogenetic relationships, population history, adaptive introgression, and breed-specific characteristics. Additionally, the moderate-coverage WGS data are suitable for structural variant (SV) detection and downstream analyses such as association mapping and the identification of SVs underlying phenotypic traits.

Indexed as

GenomeLitter SizeAnimalsGenetic VariationGenome-Wide Association StudyINDEL MutationPolymorphism, Single NucleotideSheepWhole Genome Sequencing

Identifiers

PMID40593870
PMCPMC12215492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.