Evidence map›Paper›PMID 40593825›Full record

ArticleNature communications2025

A skin-interfaced three-dimensional closed-loop sensing and therapeutic electronic wound bandage.

Xingcan Huang, Qiang Zhang, Yawen Yang, Lung Chow, Jie Ma, Guoqiang Xu, Fang Guo, Xinxin He, Zhiyuan Li, Guangyao Zhao and 26 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
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  14. Wearable Tailored Passive Radiative Cooling Textile for Flexible Electronic Integration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Xingcan Huang *Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0003-4210-2470
Qiang Zhang *Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0002-2707-0258
Yawen Yang *Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Lung Chow *Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Jie Ma *Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
Guoqiang XuDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0009-0007-5481-1422
Fang GuoSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Kowloon, Hong Kong, China.
Xinxin HeDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Zhiyuan LiDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Guangyao ZhaoDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0002-5664-4898
Jingyou SuDepartment of Chemistry, Hong Kong Baptist University, Kowloon, Hong Kong, China.
Guihuan GuoDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0009-0002-0486-0748
Jiachen WangDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Yanli JiaoDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0002-4786-9577
Zhan GaoDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0002-8465-4292
Jiyu LiDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0003-4726-4559
Jingkun ZhouDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0001-5394-4388
Chun Ki YiuDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Jian LiDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0002-9768-0932
Yi ChenDepartment of Emergency Medicine, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, China.
Pengcheng WuDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0002-7990-4234
Kuanming YaoDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0001-8744-8892
Yiming LiuDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0003-0134-1934
Dengfeng LiDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0002-8875-6974
Binbin ZhangDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Hongwei ChuDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Yue HuDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Ya HuangDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0002-0965-8226
Zhenlin ChenDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0003-2100-1363
Kangning RenDepartment of Chemistry, Hong Kong Baptist University, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0002-8563-7654
Bo FangResearch Institute for Intelligent Wearable Systems, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0002-8356-6901
Rungong YangDepartment of tissue repair and regeneration, The first medical center of Chinese PLA General Hospital, Beijing, China. yangrungong@139.com.
Heng LiDepartment of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China. heng.li@polyu.edu.hk.
Xiaoming TaoResearch Institute for Intelligent Wearable Systems, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China. xiao-ming.tao@polyu.edu.hk.ORCID http://orcid.org/0000-0002-2406-0695
Xiaohui MaDepartment of vascular and endovascular surgery, The first medical center of Chinese PLA General Hospital, Beijing, China. maxiaohui@301hospital.com.cn.
Xinge YuDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China. xingeyu@cityu.edu.hk.ORCID http://orcid.org/0000-0003-0522-1171

Funding

City University of Hong Kong (CityU) 9667221City University of Hong Kong (CityU) 9678274Innovation and Technology Commission (ITF) MRP020/21National Natural Science Foundation of China (National Science Foundation of China) 62122002Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) 7232146Shenzhen Science and Technology Innovation Commission SGDX20220530111401011
6 · The paper itself

Abstract

Chronic wound healing is a complex and long-standing problem, that has been a major and critical clinical concern around the world for years. Recent advances in digital wound dressings open new possibilities for solving the problem. Here, we report a battery-free, fully permeable, skin-adhesive, stretchable electronic wound bandage (iSAFE) for intelligent wound management. This electronic bandage exhibits superior properties in multiple features and can be conformally adhered to the skin wound. In addition, the iSAFE can accurately assess the wound conditions in-situ and thus adaptively perform localized drug release. The results from both in vitro and in vivo studies on animals prove the validity of wound monitoring, wound healing boosting and intelligent closed-loop wound management. Clinical trials on patients across age 18 to 95 with various types of wounds are performed. These results all indicate the unique and universality of the reported technology for wound monitoring and management.

Indexed as

BandagesSkinWound HealingAdolescentAdultAgedAged, 80 and overAnimalsFemaleHumansMaleMiceMiddle AgedYoung Adult

Identifiers

PMID40593825
PMCPMC12218315

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.