ArticleNature communications2025
Growth arrest is a DNA damage protection strategy in Arabidopsis.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- A potential role for DELLA signaling in global treeline formation.The New phytologist · 2026Review
- Temperature regulation of cell cycle and growth dynamics in Arabidopsis.Biochemical Society transactions · 2026Review
- The Content of Small 18S rRNA Fragments Is Regulated Developmentally and in Response to Stress in Plants.Plants (Basel, Switzerland) · 2026Article
- Transcriptome analysis reveals DNA repair-related clues associated with divergent leaf nuclear DNA diversity inFrontiers in plant science · 2026Article
- Genotype-specific transcriptomic response to drought stress in potato cultivars modulated by microbial biostimulants.BMC plant biology · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
When exposed to stress, plants reduce growth while activating defense mechanisms-a behaviour proposed to help reallocate resources and meet the energy demands required for survival. Here, we have challenged this view by mutating the cyclin-dependent kinase inhibitor SMR1 to reverse the growth arrest imposed by high DELLA levels. These plants continue growing under limited water availability but maintain the same oxidative stress tolerance and survival rates as the parental line that halted growth. However, shoot and root meristematic cells that keep dividing under drought or genotoxic stress accumulate DNA damage, frequently leading to cell death. Since the DNA lesions are observed in the apical stem cells that give rise to all plant organs, including flowers, we propose that systemic growth arrest acts as a defense strategy that plants employ not only to maximize individual fitness, but also to ensure the accurate transmission of genetic information to their progeny.
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Registered trials
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