Evidence map›Paper›PMID 40593554›Full record

ArticleNature communications2025

Chemotactic navigation in robotic swimmers via reset-free hierarchical reinforcement learning.

Tongzhao Xiong, Zhaorong Liu, Yufei Wang, Chong Jin Ong, Lailai Zhu

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Embodied Cross-Domain Intelligence in Biomedical Microrobots: A Review.Cyborg and bionic systems (Washington, D.C.) · 2026
    Review
  2. Reinforcement learning of a biflagellate model microswimmer.The European physical journal. E, Soft matter · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tongzhao XiongDepartment of Mechanical Engineering, National University of Singapore, Singapore, 117575, Singapore.ORCID http://orcid.org/0009-0004-5736-4240
Zhaorong LiuDepartment of Mechanical Engineering, National University of Singapore, Singapore, 117575, Singapore.ORCID http://orcid.org/0000-0002-3158-3902
Yufei WangDepartment of Mechanical Engineering, National University of Singapore, Singapore, 117575, Singapore.ORCID http://orcid.org/0000-0002-8850-3459
Chong Jin OngDepartment of Mechanical Engineering, National University of Singapore, Singapore, 117575, Singapore.ORCID http://orcid.org/0000-0003-0493-4575
Lailai ZhuDepartment of Mechanical Engineering, National University of Singapore, Singapore, 117575, Singapore. lailai_zhu@nus.edu.sg.ORCID http://orcid.org/0000-0002-3443-0709

Funding

Ministry of Education - Singapore (MOE) MOE-T2EP50122-0015Ministry of Education - Singapore (MOE) MOE-T2EP50221-0012
6 · The paper itself

Abstract

Microorganisms have evolved diverse strategies to propel themselves in viscous fluids, navigate complex environments, and exhibit taxis in response to stimuli. This has inspired the development of miniature robots, where artificial intelligence (AI) is playing an increasingly important role. Can AI endow these synthetic systems with intelligence akin to that honed through natural evolution? Here, we demonstrate, in silico, chemotactic navigation in a multi-link robotic model using two-level hierarchical reinforcement learning (RL). The lower-level RL allows the model-configured as a chain or ring topology-to acquire topology-adapted swimming gaits: wave propagation characteristic of flagella or body oscillation akin to an amoebae. Such chain and ring swimmers, further enabled by the higher-level RL, accomplish chemotactic navigation in prototypical biologically relevant scenarios that feature conflicting chemoattractants, pursuing a swimming bacterial mimic, steering in vortical flows, and squeezing through tight constrictions. Additionally, we achieve reset-free RL under partial observability, where simulated robots rely solely on local scalar observations rather than global or vectorial data. This advancement illuminates potential solutions for overcoming persistent challenges of manual resets and partial observability in real-world microrobotic RL.

Indexed as

Artificial IntelligenceChemotaxisRoboticsSwimmingComputer SimulationFlagellaModels, Biological

Identifiers

PMID40593554
PMCPMC12215520

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.