Evidence map›Paper›PMID 40593369›Full record

ArticleInsights into imaging2025

Predictive value of subacromial motion metrics for the effectiveness of ultrasound-guided dual-target injection: a longitudinal follow-up cohort trial.

Wei-Ting Wu, Che-Yu Lin, Yi-Chung Shu, Lan-Rong Chen, Levent Özçakar, Ke-Vin Chang

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04219527 (Quantitative Assessment and Dual-target Intervention for Impinged and Frozen Shoulders), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04219527 naunknown statusnot on this map

Quantitative Assessment and Dual-target Intervention for Impinged and Frozen Shoulders: A Longitudinal Study of Dual-target Ultrasound Guided Corticosteroid Injection for Shoulder Impingement Syndrome

TypeinterventionalSponsorNational Taiwan University HospitalRan2020 to 2022Enrolled210ConditionsShoulder ImpingementArmsDual-target injection
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei-Ting WuDepartment of Physical Medicine and Rehabilitation and Community and Geriatric Research Center, National Taiwan University Hospital, Bei-Hu Branch, Taipei City, Taiwan.
Che-Yu LinInstitute of Applied Mechanics, College of Engineering, National Taiwan University, Taipei, Taiwan.
Yi-Chung ShuInstitute of Applied Mechanics, College of Engineering, National Taiwan University, Taipei, Taiwan.
Lan-Rong ChenDepartment of Physical Medicine and Rehabilitation and Community and Geriatric Research Center, National Taiwan University Hospital, Bei-Hu Branch, Taipei City, Taiwan.
Levent ÖzçakarDepartment of Physical and Rehabilitation Medicine, Hacettepe University Medical School, Ankara, Turkey.
Ke-Vin ChangDepartment of Physical Medicine and Rehabilitation and Community and Geriatric Research Center, National Taiwan University Hospital, Bei-Hu Branch, Taipei City, Taiwan. kvchang011@gmail.com.ORCID http://orcid.org/0000-0002-7558-5651

Funding

Ministry of Science and Technology, Taiwan MOST 106-2314-B-002-180-MY3Ministry of Science and Technology, Taiwan MOST 109-2314-B-002-114-MY3National Science and Technology, Taiwan NSTC 112-2314-B-002-134National Science and Technology, Taiwan NSTC 113-2314-B-002 -208 -MY2National Science and Technology, Taiwan NSTC 113-2314-B-002 -209 -MY2
6 · The paper itself

Abstract

objectiveSubacromial impingement syndrome (SIS) frequently causes shoulder pain. This study aimed to (1) assess the predictive utility of quantitative dynamic subacromial ultrasound for ultrasound-guided dual-target injections and (2) compare the long-term efficacy of dual-target injections with standard subdeltoid-subacromial injections in SIS patients.

methodsPatients with SIS received 40 mg of triamcinolone acetonide via ultrasound-guided dual-target injections (subdeltoid-subacromial bursa and long head of the biceps brachii tendon). Clinical assessments and static/dynamic ultrasound were performed at baseline and 4 weeks post-procedure. Minimal vertical acromiohumeral distance (mVAHD) was measured by tracing the humeral greater tuberosity against the acromion. A historical cohort receiving standard subdeltoid-subacromial corticosteroid injections was used for comparison.

resultsOf 90 patients receiving dual-target injections, 70 (77.7%) achieved early treatment success. An enlarged minimal mVAHD was associated with success, except during the abduction phase in the full-can posture. Among these 70 patients, 25 (35.7%) had shoulder pain recurrence requiring repeat injections, linked to a decreased mVAHD across all phases and postures. Compared to 90 patients in a historical cohort receiving standard subdeltoid-subacromial injections, the dual-target group had a significantly longer mean time to pain recurrence (309.1 ± 130.1 days vs. 267.5 ± 184.2 days, p = 0.03).

conclusionDynamic ultrasound metrics, including mVAHD, predict early success and pain recurrence following dual-target injections in SIS. Dual-target injections offer a longer duration of effectiveness compared to standard subdeltoid-subacromial injections. Future research should explore the predictive value of mVAHD with deep learning algorithms and evaluate the approach in adhesive capsulitis.

trial registrationClinicalTrials.gov (NCT04219527). Registered on 27 December 2019, https://clinicaltrials.gov/study/NCT04219527 . CRITICAL RELEVANCE STATEMENT: Dynamic ultrasound metrics predict early success and pain recurrence following dual-target injections in SIS, offering a longer duration of effectiveness compared to standard subdeltoid-subacromial injections. KEY POINTS: Dynamic ultrasound metrics predict injection success and pain recurrence in impingement. Dual-target injections offer a longer duration of effectiveness than standard injections. Future research should assess deep learning's predictive value in adhesive capsulitis.

Indexed as

CorticosteroidRehabilitationRotator intervalShoulder impingement syndromeUltrasound

Identifiers

PMID40593369
PMCPMC12214097

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.