Evidence map›Paper›PMID 40593253›Full record

ReviewAdvanced biotechnology2025

Single-cell omics in plant biology: mechanistic insights and applications for crop improvement.

Tao Zhu, Tianxiang Li, Peitao Lü, Chenlong Li

Abstract readReview
In one paragraph

Review in Advanced biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
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  9. Review
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  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tao Zhu *State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China.
Tianxiang Li *National Key Laboratory for Tropical Crop Breeding, Institute of Tropical Bioscience and Biotechnology &, Sanya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Sanya, 572024, China.
Peitao LüNational Key Laboratory for Tropical Crop Breeding, Institute of Tropical Bioscience and Biotechnology &, Sanya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Sanya, 572024, China. lvpeitao@itbb.org.cn.
Chenlong LiState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China. lichlong3@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0003-3405-6056

Funding

Central Public-interest Scientific Institution Basal Research Fund for Chinese Academy of Tropical Agricultural Sciences 1630052024024Key Technologies Research and Development Program 2024YFD1200800National Natural Science Foundation of China 32270362National Natural Science Foundation of China 32470346Project of National Key Laboratory for Tropical Crop Breeding NKLTCBCXTD26Project of National Key Laboratory for Tropical Crop Breeding NKLTCB-RC202402
6 · The paper itself

Abstract

In recent years, single-cell omics technologies have significantly advanced plant and agricultural research, providing transformative insights into plant development, cellular heterogeneity, and environmental response mechanisms. Traditional bulk-level analyses often obscure differences between individual cells, whereas single-cell RNA sequencing (scRNA-seq) and single-nucleus RNA sequencing (snRNA-seq) now reveal unique expression profiles across distinct cell populations, facilitating the identification of novel cell types and elucidation of gene regulatory networks. Additionally, epigenomic approaches like single-nucleus ATAC sequencing (snATAC-seq) offer a deeper understanding of chromatin accessibility and its complex relationship with gene regulation. These technologies have seen widespread application in model plants such as Arabidopsis thaliana, as well as in major crops and horticultural plants, providing essential data for crop improvement and breeding strategies. Moving forward, with the continued development and integration of single-cell multi-omics technologies, there will be greater depth of insight into cell-type-specific regulation and complex trait analysis, bringing new opportunities for sustainable agriculture and crop improvement.

Indexed as

Biology FindingsCropsHorticultural plantsPlantsPlant single-cell omicsSingle-cell transcriptomics

Identifiers

PMID40593253
PMCPMC12214168

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.