Evidence map›Paper›PMID 40593244›Full record

ArticleWorld journal of microbiology & biotechnology2025

Sonoporation-enhanced the antibacterial efficacy of aminoglycosides against Gram-negative persisters.

Hongyi Chen, Jingkai Wang, Fang Han, Chen Guo, Xinmiao Fu, Zhiqiang Zhang, Yizhi Song

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hongyi ChenDivision of Life Sciences and Medicine, School of Biomedical Engineering (Suzhou), University of Science and Technology of China, Suzhou, Jiangsu Province, 215163, China.
Jingkai WangSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu Province, 215163, China.
Fang HanDivision of Life Sciences and Medicine, School of Biomedical Engineering (Suzhou), University of Science and Technology of China, Suzhou, Jiangsu Province, 215163, China.
Chen GuoDivision of Life Sciences and Medicine, School of Biomedical Engineering (Suzhou), University of Science and Technology of China, Suzhou, Jiangsu Province, 215163, China.
Xinmiao FuProvincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Sciences, Fujian Normal University, Fuzhou, Fujian Province, 350117, China.
Zhiqiang ZhangDivision of Life Sciences and Medicine, School of Biomedical Engineering (Suzhou), University of Science and Technology of China, Suzhou, Jiangsu Province, 215163, China. zhangzq@sibet.ac.cn.
Yizhi SongDivision of Life Sciences and Medicine, School of Biomedical Engineering (Suzhou), University of Science and Technology of China, Suzhou, Jiangsu Province, 215163, China. songyz@sibet.ac.cn.

Funding

Gusu Leading Talent Project ZXL2021422the National Natural Science Foundation of China 32170713the Natural Science Foundation of Jiangsu Province BK20230224the Suzhou Municipal Science and Technology Bureau Project SJC2021017
6 · The paper itself

Abstract

Bacterial persisters pose a significant challenge to antibiotic therapy, often causing treatment failure and chronic infections. Improving antibiotic efficacy against persisters is thus clinically crucial. In this study, we developed a low-frequency and low-intensity ultrasound system (40 kHz, 0.2 W/cm

Indexed as

AminoglycosidesAnti-Bacterial AgentsGram-Negative BacteriaAcinetobacter baumanniiCell Membrane PermeabilityEscherichia coliMicrobial Sensitivity TestsPseudomonas aeruginosaUltrasonic WavesAminoglycosidesAnti-Bacterial AgentsAminoglycosideAntimicrobial resistanceBacteria persistersMechanosensitive channelMembrane permeabilityUltrasound

Identifiers

PMID40593244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.