ArticleScientific reports2025
Genetic diversity, population structure, and cannabinoid variation in feral Cannabis sativa germplasm from the United States.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Genetic architecture of phenological, morphological, and phytochemical traits in Cannabis landraces.The plant genome · 2026Article
- Genetic Diversity and Core Germplasm Development in Yunnan Tartary Buckwheat Based on Phenotypic and SNP Data.Plants (Basel, Switzerland) · 2026Article
- Micropropagation of Cannabis sativa: genetic and epigenetic stability assessment over multiple generations.Journal of cannabis research · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Cannabis sativa is one of the earliest plants to be domesticated for fiber, food and medicine. Seed from Cannabis grown for industrial purposes during the 18th through 20th centuries have escaped production and established feralized populations across the United States. To maximize the potential of feral Cannabis germplasm, determining the genetic structure and cannabinoid profile is crucial for selection and breeding of new compliant regionally adapted hemp cultivars. To resolve this, a collection of feral Cannabis, comprising 760 plants across twelve US states were sequenced using Genotyping-by-Sequencings (GBS), genotyped at the cannabinoid synthase (CBDAS) gene, and subject to gas chromatography-mass spectrometry (GC-MS) to assess cannabinoid profiles. Clustering analyses by ADMIXTURE and Principal Component Analysis (PCA) stratified the germplasm into five clusters (Mississippi-River, West North Central-b, West North Central-a, New York, and Indiana). The cannabinoid genotyping assay resolved the feral collections into Type I - B2/B2 (6%), Type II - B2/B1 (15%), and Type III - B1/B1 (78%). Total cannabinoid content ranged from 0.21 to 4.73%. The assessment of genetic diversity, population structure, and cannabinoid profile of the US feral Cannabis collection provides critical information and germplasm resources to develop new and improve existing hemp cultivars.
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