ArticleScientific reports2025
NaLRR-RK4 mediates MAPK signaling to enhance plant defense against Alternaria alternata in Nicotiana attenuata.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study investigates the role of NaLRR-RK4 in plant defense against Alternaria alternata in Nicotiana attenuata, focusing on the differential gene expression in wild-type (WT, NaLRR-RK4 expressed) and NaLRR-RK4-silenced (RNAi) plants upon inoculation. Transcriptomic sequencing was conducted to analyze the expression of genes in WT and RNAi plants under Alternaria alternata infection and non-infection conditions, aiming to identify the pathways influenced by NaLRR-RK4 in conferring resistance to A. alternata. The activation of MAPK signaling in WT plants, including the upregulation of WRKY33, PR1, and ethylene- and ABA-responsive genes, plays a crucial role in enhancing resistance against A. alternata. In contrast, RNAi-treated plants exhibited reduced activation of these genes, highlighting the essential role of NaLRR-RK4 in initiating effective defense responses. NaLRR-RK4 functions as a key regulator of MAPK signaling, mediating plant defense against A. alternata through the coordinated activation of WRKY33, PR1, and ethylene- and ABA-responsive genes.
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