Evidence map›Paper›PMID 40592941›Full record

ArticleScientific reports2025

Blood supply of the human carotid body.

Atieh Seyedian Moghaddam, Stefan H Geyer, Berna Dogan, Paata Pruidze, Jeremias T Weninger, Karoline M Schwendt, Wolfgang J Weninger

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Atieh Seyedian MoghaddamDivision of Anatomy, Center for Anatomy and Cell Biology, RPMI, MIC, Medical University of Vienna, Währinger Strasse 13, 1090, Vienna, Austria. atieh.seyedianmoghaddam@meduniwien.ac.at.
Stefan H GeyerDivision of Anatomy, Center for Anatomy and Cell Biology, RPMI, MIC, Medical University of Vienna, Währinger Strasse 13, 1090, Vienna, Austria.
Berna DoganDepartment of Anatomy, Faculty of Medicine, Tokat Gaziosmanpasa University, Tokat, Turkey.
Paata PruidzeDivision of Anatomy, Center for Anatomy and Cell Biology, RPMI, MIC, Medical University of Vienna, Währinger Strasse 13, 1090, Vienna, Austria.
Jeremias T WeningerDivision of Anatomy, Center for Anatomy and Cell Biology, RPMI, MIC, Medical University of Vienna, Währinger Strasse 13, 1090, Vienna, Austria.
Karoline M SchwendtDivision of Anatomy, Center for Anatomy and Cell Biology, RPMI, MIC, Medical University of Vienna, Währinger Strasse 13, 1090, Vienna, Austria.
Wolfgang J WeningerDivision of Anatomy, Center for Anatomy and Cell Biology, RPMI, MIC, Medical University of Vienna, Währinger Strasse 13, 1090, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glomic arteries (GAs) supply the carotid body (CB), a chemosensory organ at the carotid bifurcation. Accurate knowledge of GA anatomy is essential for CB surgery and understanding the impact of carotid artery atherosclerosis on breathing and blood pressure regulation. This study aims to provide comprehensive, statistically significant data on the number, origin, topology, length, and complexity of human GAs. Employing high-resolution episcopic microscopy (HREM), the Amira® software, and statistics, 120 CBs from 30 female and 30 male body donors were analyzed. CBs were located at the anterior (7.5%), posterior (66.7%), and above the central carotid bifurcation (25.8%). They were supplied by up to five GAs; 25% by a single, and 54% by two GAs. Sixty percent of GAs originated from the external carotid artery. In 85% of CBs receiving multiple GAs, at least one arose from this artery. The average tortuosity value of the GAs was 1.56, and their mean length was 2.36 mm, with male and left-sided GAs being significantly longer. This large-scale, systematic study provides high-resolution 3D data and challenges existing anatomic GA descriptions. It offers a solid foundation for studying carotid artery atherosclerosis's physiological and pathological implications, and advancing the treatment of CB tumors.

Indexed as

Carotid BodyAdultAgedCarotid ArteriesFemaleHumansMaleMiddle AgedAtherosclerosisCarotid bifurcationCarotid sinusHigh-resolution episcopic microscopy (HREM)

Identifiers

PMID40592941
PMCPMC12214507

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.