Evidence map›Paper›PMID 40592935›Full record

ArticleScientific reports2025

Theory of mind and impulsivity mediate the relationship between anxiety and non-suicidal self-injury in adolescents with depressive disorder.

Fangjun Huang, Jing Zeng, Shiwei Huang, Tiebang Liu, Guojun Wang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Fangjun HuangShenzhen Clinical Research Center for Mental Disorders, Shenzhen Mental Health Center/Shenzhen Kangning Hospital, Shenzhen City, 518118, Guangdong Province, China.
Jing ZengShenzhen Clinical Research Center for Mental Disorders, Shenzhen Mental Health Center/Shenzhen Kangning Hospital, Shenzhen City, 518118, Guangdong Province, China.
Shiwei HuangShenzhen Clinical Research Center for Mental Disorders, Shenzhen Mental Health Center/Shenzhen Kangning Hospital, Shenzhen City, 518118, Guangdong Province, China.
Tiebang LiuShenzhen Clinical Research Center for Mental Disorders, Shenzhen Mental Health Center/Shenzhen Kangning Hospital, Shenzhen City, 518118, Guangdong Province, China.
Guojun WangDepartment of Clinical Psychological Research, Nanning Fifth People's Hospital, Nanning City, 530001, Guangxi Province, China. guojun-wang@hotmail.com.

Funding

Sanming Project of Medicine in Shenzhen No.SZSM202311026Science and Technology Planning Project of Shenzen Municipality No.20210617155253001Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties No.SZGSP013Shenzhen Key Medical Discipline Construction Fund No.SZXK072
6 · The paper itself

Abstract

Impairment in Theory of Mind (ToM) may serve as a mediator in the relationship between anxiety, depression emotions and non-suicidal self-injury (NSSI) in adolescent patients with depressive disorders. This study aimed to examine the mediating roles of ToM and impulsivity in the link between anxiety, depression, and NSSI in first-time hospitalized adolescents with depressive disorders. A total of 52 adolescents patients were recruited from Shenzhen Kangning Hospital. Anxiety, depression, impulsivity, NSSI, cognitive ToM, and affective ToM were assessed using the Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, Barratt Impulsivity Scale, Adolescent Self-Harm Scale, Yoni task, and Hinting task. A structural equation model was developed using AMOS 24.0 to investigate the underlying mechanisms of NSSI. Our results indicate that anxiety not only directly contributes to NSSI but also exerts its influence through two indirect pathways: impairing cognitive ToM and disrupting affective ToM, which heightens impulsivity. These mechanisms may further increase the likelihood of NSSI (CMIN = 5.168, CMIN/DF = 1.292, P = 0.270, GFI = 0.964, AGFI = 0.864, TLI = 0.929, RMSEA = 0.076). These results highlight the importance of interventions aimed at reducing anxiety and impulsivity while enhancing ToM abilities to help mitigate NSSI risk in adolescents with depressive disorders.

Indexed as

AnxietyDepressive DisorderImpulsive BehaviorSelf-Injurious BehaviorTheory of MindAdolescentFemaleHumansMaleAdolescentDepressive disorderImpulsivityNon-suicidal self-injuryTheory of mind

Identifiers

PMID40592935
PMCPMC12215078

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.