ReviewCell death & disease2025
Current understanding of eryptosis: mechanisms, physiological functions, role in disease, pharmacological applications, and nomenclature recommendations.
Abstract readReview
In one paragraph
Review in Cell death & disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Tasisulam-induced suicidal death of human erythrocytes.Biochemistry and biophysics reports · 2026Article
- Metabolic Exhaustion, p38 MAPK/Rac1 GTPase/MLKL Signaling, and Ca2+ Influx Mediate Solasodine-Triggered Eryptosis.Physiological research · 2026Article
- Curcumin's Protective Effects Against HMolecules (Basel, Switzerland) · 2026Review
- Surface cues shape procoagulant properties of amyloidogenic microclots.Cell death & disease · 2026Review
- Biomimetic Targeted Drug Delivery for Liver Failure in Abdominal Sepsis: Focus on Autologous Erythrocyte Ghosts.International journal of molecular sciences · 2026Review
- Association of Anemia Severity with Distinct Microbial and Inflammatory Signatures in Patients Receiving Vancomycin.Healthcare (Basel, Switzerland) · 2026Article
- Stimulation of Eryptosis and Hemolysis by Adrenic Acid Involves Oxidative Stress, Calcium Elevation, and Metabolic Collapse.International journal of molecular sciences · 2026Article
- Geraniol Exerts Cytotoxic Effects in Red Cells Through CaMolecules (Basel, Switzerland) · 2026Article
- Quercetin mitigates size-dependent oxidative and metabolic toxicity of citrate-coated silver nanoparticles in human erythrocytes.Archives of toxicology · 2026Article
- Discovery of spectosis supports the key role of caspase-8 in determining the type of cell death in mature erythrocytes and erythrocyte death-driven immunogenicity.Cell death discovery · 2026Article
- RTX-family toxin EhxA drives morphological remodeling and thrombogenesis in RBCs during enterohemorrhagicScience advances · 2026Article
- Ubiquitination and degradation of CD47 enhances macrophage phagocytosis of hemolytic erythrocytes.iScience · 2026Article
- Eryptosis in Acute Patients: A Hypothesis on Its Potential Clinical Impact and Current Gaps in Evidence.Current issues in molecular biology · 2026Review
- Isoniazid subverting erythrocyte homeostasis: implications for tuberculosis therapy.Frontiers in pharmacology · 2026Article
- Anemia, as an adverse event during chemoradiotherapy for head and neck cancer, contributes to a reduction in swallowing muscle mass and leads to dysphagia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Observational
- Redefining the concept of erythrocyte senescence: is eryptosis fundamentally different from erythrocyte senescence.GeroScience · 2025Review
- Article
- Eryptosis in Liver Diseases: Contribution to Anemia and Hypercoagulation.Medical sciences (Basel, Switzerland) · 2025Review
- Not-So-Rare Defects of RBC Lipidic Composition: Four New Cases of Flippase Deficiency Due toInternational journal of molecular sciences · 2025Article
- Eryptosis in renal anemia: mechanisms, clinical implications, and therapeutic targeting.Frontiers in pharmacology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Anton TkachenkoDepartment of Cryobiochemistry, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine. as.tkachenko@knmu.edu.ua.ORCID http://orcid.org/0000-0002-1029-1636
Mohammad A AlfhiliChair of Medical and Molecular Genetics Research, Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Jawaher AlsughayyirDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Alessandro AttanzioDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy.ORCID http://orcid.org/0000-0002-6622-028X
Abdulla Al Mamun BhuyanDepartment of Veterinary and Animal Sciences, University of Rajshahi-6205, Rajshahi, Bangladesh.
Bożena BukowskaDepartment of Biophysics of Environmental Pollution, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.ORCID http://orcid.org/0000-0003-3044-2953
Antonio CillaNutrition and Food Science Area, Faculty of Pharmacy and Food Sciences, University of Valencia, Burjassot, Spain.
Martha A Quintanar-EscorzaMedicine and Nutrition Faculty, Universidad Juárez del Estado de Durango, Durango, Dgo, México.
Michael FöllerDepartment of Physiology, University of Hohenheim, Stuttgart, Germany.ORCID http://orcid.org/0000-0003-2074-4827
Ondrej HavranekBIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic.ORCID http://orcid.org/0000-0001-5826-3557
Kashif JilaniDepartment of Biochemistry, University of Agriculture, Faisalabad, Pakistan.
Anatolii OnishchenkoDepartment of Cryobiochemistry, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine.
Etheresia PretoriusDepartment of Physiological Sciences, Faculty of Science, Stellenbosch University, Stellenbosch, South Africa.ORCID http://orcid.org/0000-0002-9108-2384
Volodymyr ProkopiukDepartment of Cryobiochemistry, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine.
Ignazio RestivoDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy.ORCID http://orcid.org/0000-0003-1833-2356
Luisa TesoriereDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy.
Grazia Maria VirzìDepartment of Nephrology, Dialysis and Transplant, St Bortolo Hospital, Vicenza, Italy.
Thomas WiederInstitute of Physiology I, Eberhard Karls University Tübingen, Tübingen, Germany.
Funding
European Hematology Association (EHA) EHA Ukraine Bridge Funding
Abstract
Early studies have shown that erythrocytes have caspase-3 and caspase-8 and are capable of dying through an apoptotic-like cell death triggered by Ca
Indexed as
EryptosisErythrocytesAnimalsApoptosisCalciumHumansTerminology as TopicCalcium
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.