Evidence map›Paper›PMID 40592545›Full record

ArticleMolecular pharmaceutics2025

Caulerpin Delivery via Pluronic-Free Cubosomes: Unlocking the Therapeutic Potential of a Pigment from an Invasive Marine Algae.

Karolina Krautforst, Julita Kulbacka, Marco Fornasier, Rita Mocci, Andrea Porcheddu, Antonio Pusceddu, Davide Moccia, Sergio Murgia, Urszula Bazylińska

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Karolina KrautforstDepartment of Chemical and Geological Sciences, University of Cagliari, s.s. 554 bivio Sestu, I-09042 Monserrato, CA, Italy.
Julita KulbackaDepartment of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211 A, 50-556 Wroclaw, Poland.
Marco FornasierCSGI, Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase, via della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy.ORCID 0000-0002-5788-6741
Rita MocciDepartment of Chemical and Geological Sciences, University of Cagliari, s.s. 554 bivio Sestu, I-09042 Monserrato, CA, Italy.
Andrea PorchedduDepartment of Chemical and Geological Sciences, University of Cagliari, s.s. 554 bivio Sestu, I-09042 Monserrato, CA, Italy.ORCID 0000-0001-7367-1102
Antonio PuscedduDepartment of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria Monserrato, S.P. 8 Km 0.700, I-09042 Monserrato, CA, Italy.
Davide MocciaDepartment of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria Monserrato, S.P. 8 Km 0.700, I-09042 Monserrato, CA, Italy.
Sergio MurgiaCSGI, Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase, via della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy.ORCID 0000-0002-9986-0638
Urszula BazylińskaDepartment of Physical and Quantum Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer remains one of the deadliest cancers due to its resistance to conventional therapies, necessitating the development of novel treatment strategies. This study investigates the anticancer potential of caulerpin, a bisindole alkaloid derived from the invasive marine alga

Indexed as

CaulerpaIndolesNanoparticlesPancreatic NeoplasmsAntineoplastic AgentsApoptosisCell Line, TumorDrug Delivery SystemsHumansPoloxamerAntineoplastic AgentsIndolesPoloxameralgaeanticancercaulerpincubosomesnanocarrierspancreatic tumor

Identifiers

PMID40592545
PMCPMC12326354

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.