Evidence map›Paper›PMID 40591931›Full record

ArticleAmerican journal of respiratory cell and molecular biology2025

Surfactant Protein (SP)-A Benefits Over SP-A Mutant: A Preliminary Study for Interstitial Lung Disease Treatment.

Tifenn Desroziers, Yohan Soreze, Marie Legendre, Florence Dastot Le Moal, Valérie Nau, Serge Amselem, Irina Giurgea, Sonia Karabina, Camille Louvrier, Nadia Nathan

Abstract read
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In one paragraph

Article in American journal of respiratory cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. From Protein Folding to Precision Therapy: Surfactant Protein A in the Spotlight.American journal of respiratory cell and molecular biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Tifenn DesroziersInserm UMR_S933, Laboratory of Childhood Genetic Diseases, Sorbonne Université, Armand Trousseau Hospital, Paris, France.ORCID 0000-0001-7071-5173
Yohan SorezeInserm UMR_S933, Laboratory of Childhood Genetic Diseases, Sorbonne Université, Armand Trousseau Hospital, Paris, France.ORCID 0000-0001-7803-5113
Marie LegendreInserm UMR_S933, Laboratory of Childhood Genetic Diseases, Sorbonne Université, Armand Trousseau Hospital, Paris, France.ORCID 0000-0003-2178-0846
Florence Dastot Le MoalMolecular Genetics Unit, Sorbonne Université, Assistance Publique - Hôpitaux de Paris, Armand Trousseau Hospital, Paris, France; and.ORCID 0000-0001-7368-5344
Valérie NauMolecular Genetics Unit, Sorbonne Université, Assistance Publique - Hôpitaux de Paris, Armand Trousseau Hospital, Paris, France; and.ORCID 0009-0003-7712-1943
Serge AmselemInserm UMR_S933, Laboratory of Childhood Genetic Diseases, Sorbonne Université, Armand Trousseau Hospital, Paris, France.ORCID 0000-0001-9506-3968
Irina GiurgeaInserm UMR_S933, Laboratory of Childhood Genetic Diseases, Sorbonne Université, Armand Trousseau Hospital, Paris, France.ORCID 0000-0002-5035-2958
Sonia KarabinaInserm UMR_S933, Laboratory of Childhood Genetic Diseases, Sorbonne Université, Armand Trousseau Hospital, Paris, France.ORCID 0000-0002-1865-6185
Camille LouvrierInserm UMR_S933, Laboratory of Childhood Genetic Diseases, Sorbonne Université, Armand Trousseau Hospital, Paris, France.ORCID 0000-0003-2105-1117
Nadia NathanInserm UMR_S933, Laboratory of Childhood Genetic Diseases, Sorbonne Université, Armand Trousseau Hospital, Paris, France.ORCID 0000-0001-5149-7975

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surfactant protein (SP)-A, an octadecamer composed of SP-A1 and SP-A2, is secreted into the alveolar space. Heterozygous variations in

Indexed as

Lung Diseases, InterstitialMutationPulmonary Surfactant-Associated Protein AHEK293 CellsHumansProtein MultimerizationPulmonary Surfactant-Associated Protein ASFTPA1 protein, humanSFTPA2 protein, humaninterstitial lung diseaseoligomerizationSP-Asurfactanttreatment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.