Evidence map›Paper›PMID 40591889›Full record

ArticleACS applied materials & interfaces2025

Hybrid Aptamer Molecularly Imprinted Polymer Nanoparticles for Reducing Oxidized Low-Density Lipoprotein Internalization by Macrophages.

Suticha Chunta, Soemwit Khongwichit, Piyawut Swangphon, Maliwan Srisuk, Peter A Lieberzeit, Maliwan Amatatongchai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Suticha ChuntaFaculty of Medical Technology, Prince of Songkla University, Songkhla 90110, Thailand.ORCID 0000-0002-5154-6439
Soemwit KhongwichitFaculty of Medical Technology, Prince of Songkla University, Songkhla 90110, Thailand.
Piyawut SwangphonFaculty of Medical Technology, Prince of Songkla University, Songkhla 90110, Thailand.
Maliwan SrisukDivision of Biological Science, Faculty of Science, Prince of Songkla University, Songkhla 90110, Thailand.
Peter A LieberzeitFaculty for Chemistry, Department of Physical Chemistry, University of Vienna, Vienna 1090, Austria.ORCID 0000-0003-1596-0584
Maliwan AmatatongchaiDepartment of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ubon Ratchathani University, Ubon Ratchathani 34190, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidized low-density lipoprotein (oxLDL) is the most typical physiological trigger for the formation of macrophage foam cells, leading to atherosclerosis and coronary heart disease. The inhibition of internalized oxLDL in macrophages is a proven effective strategy for the prevention of atherosclerosis. A hybrid aptamer-molecularly imprinted polymer nanoparticle (AP-MIP NP) is a novel synthetic, biocompatible, selective material that can bind directly to oxLDL and decrease its uptake by macrophages by 62 ± 2% compared to oxLDL alone at a concentration of 8.25 × 10

Indexed as

Aptamers, NucleotideLipoproteins, LDLMacrophagesMolecularly Imprinted PolymersNanoparticlesAnimalsFoam CellsHumansMiceRAW 264.7 CellsAptamers, NucleotideLipoproteins, LDLMolecularly Imprinted Polymersoxidized low density lipoproteinaptamermolecularly imprinted polymernanoparticle compositeoxidized low-density lipoproteinprotective agent

Identifiers

PMID40591889
PMCPMC12278217

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.