Evidence map›Paper›PMID 40591673›Full record

ArticlePloS one2025

Barriers and perceptions of WHONET/BacLink adoption in Nepal: A qualitative study of clinical microbiology laboratories.

Sanju Maharjan, Patrick Gallagher, Manish Gautam, Sanjay Gautam, Manisha Budhathoki, Reena Mukhiya, Smirti Kattel, Amit Bhandari, Hea Sun Joh, Ahmed Taha Aboushady and 8 more

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Sanju MaharjanAnweshan Private Limited, Lalitpur, Nepal.
Patrick GallagherPublic Health Surveillance Group LLC, New Jersey, United States of America.
Manish GautamAnweshan Private Limited, Lalitpur, Nepal.
Sanjay GautamInternational Vaccine Institute, SNU Research Park, Gwanak-gu, Seoul, Korea, Republic of Korea.ORCID https://orcid.org/0000-0003-0187-6429
Manisha BudhathokiAnweshan Private Limited, Lalitpur, Nepal.
Reena MukhiyaBurnet Institute, Melbourne, Australia.
Smirti KattelUniversity of the West of Scotland, London Campus, London.
Amit BhandariIndependent Health Expert, Kathmandu, Nepal.
Hea Sun JohInternational Vaccine Institute, SNU Research Park, Gwanak-gu, Seoul, Korea, Republic of Korea.
Ahmed Taha AboushadyBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0002-8245-6591
Raphaël M ZellwegerInternational Vaccine Institute, SNU Research Park, Gwanak-gu, Seoul, Korea, Republic of Korea.
Madan Kumar UpadhyayaQuality Standard and Regulation Division, Ministry of Health and Population, Government of Nepal, Kathmandu, Nepal.
Runa JhaNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal.
Jyoti AcharyaNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal.ORCID https://orcid.org/0000-0002-0235-8538
William R MacWrightPublic Health Surveillance Group LLC, New Jersey, United States of America.
Florian MarksPublic Health Surveillance Group LLC, New Jersey, United States of America.
John StellingIndependent Health Expert, Kathmandu, Nepal.
Nimesh PoudyalInternational Vaccine Institute, SNU Research Park, Gwanak-gu, Seoul, Korea, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe International Vaccine Institute-led CAPTURA (Capturing Data on Antimicrobial Resistance Patterns and Trends in Use in Regions of Asia) project delivered capacity building activities to strengthen antimicrobial resistance surveillance activities in Nepal.

methodsThe CAPTURA project trained 97 laboratory personnel from 19 hospitals on the use of WHONET/BacLink software to manage microbiology data in Nepal during 2020-2021. Approximately two years later, the trainees were followed up by phone to assess implementation status and effectiveness of the training. An inductive approach was used for coding and categorization of their response, and themes were generated for analysis. Trainees from ten hospitals agreed to respond regarding their experience.

resultsWe found that two out of the ten hospitals were using the WHONET/BacLink software, with one each within and outside the national AMR surveillance network. The remaining eight hospitals never implemented the system despite receiving the training. Key barriers to implementation included, hospital administration prioritizing other interoperable software, limited ongoing training, inability to export data from an LIS, limited real-time assistance with technical issues, and poor confidence in analyzing data. In addition, limited human resources and minimal capacity-building activities resulted in a lack of confidence in using the system independently, which were also identified as barriers.

conclusionImplementing WHONET/BacLink software in hospital settings can be challenging due to various factors, including a lack of knowledge and confidence among users, a lack of time and human resources to use the software effectively, and a lack of interoperability with other hospital management systems. Real-time support and follow-up activities potentially reinforce the skills and knowledge delivered during the training.

Indexed as

Laboratories, ClinicalSoftwareHospitalsHumansNepalQualitative Research

Identifiers

PMID40591673
PMCPMC12212552

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.