Observational studyPloS one2025
Prognostic value of the lactate-albumin ratio in trauma: A comparison with shock index and injury severity score.
Observational study in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Lactate-to-albumin ratio, C-reactive protein-to-albumin ratio, and prognostic nutritional index in acute and critical care: A focused mini-review.World journal of critical care medicine · 2026Review
- Developing and validating a lactate-to-albumin ratio-enhanced score for mortality prediction in ICU patients with acute pulmonary embolism: a multi-cohort study.Frontiers in medicine · 2026Article
- Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to assess the predictive value of lactate-to-albumin ratio (LAR) for in-hospital mortality and massive transfusion (MT) in severe trauma cases. This retrospective, observational, single-center study included patients who presented to a trauma center between 2016 and 2022. The primary outcome was in-hospital mortality, and the secondary outcome was MT. Logistic regression analysis was performed to determine whether LAR was an independent risk factor. The area under the receiver operating characteristic (AUROC) curve was calculated to evaluate the predictive value of LAR. In total, 5,304 patients were included. Logistic regression analysis identified LAR as an independent risk factor for in-hospital mortality. The AUROCs for predicting in-hospital mortality using LAR, Injury Severity Score (ISS), and Shock Index (SI) were 0.74 (95% confidence interval [CI], 0.73-0.75), 0.78 (95% CI, 0.77-0.779), and 0.51 (95% CI, 0.49-0.52), respectively. LAR was statistically significant compared with SI (p < 0.0001; 95% CI, 0.194-0.276) and similar to ISS (p = 0.0039; 95% CI, 0.0115-0.0604). LAR (0.84; 95% CI, 0.83-0.85) demonstrated superior predictive power for MT compared with SI (0.68; 95% CI, 0.67-0.70) and ISS (0.79; 95% CI, 0.78-0.80). LAR demonstrates a superior predictive ability for in-hospital mortality and MT.
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Registered trials
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