Evidence map›Paper›PMID 40591601›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Epigenetic cellular memory in

Elisabeth Vatareck, Tim Rick, Nicolas Oswaldo Gomez, Arnab Bandyopadhyay, Janina Kramer, Dmytro Strunin, Jelena Erdmann, Oliver Hartmann, Kathrin Alpers, Christian Boedeker and 5 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Epigenetic cellular memory inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Elisabeth Vatareck *Department of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.
Tim Rick *Department of Clinical Microbiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen 2100, Denmark.
Nicolas Oswaldo Gomez *Department of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.ORCID 0000-0001-5723-886X
Arnab Bandyopadhyay *Department of Systems Immunology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.ORCID 0000-0002-5149-1714
Janina KramerDepartment of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.ORCID 0009-0004-8975-5991
Dmytro StruninDepartment of Clinical Microbiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen 2100, Denmark.ORCID 0009-0000-1379-9227
Jelena ErdmannDepartment of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.ORCID 0000-0001-6928-3326
Oliver HartmannDepartment of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.ORCID 0009-0006-2905-5322
Kathrin AlpersDepartment of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.
Christian BoedekerLeibniz Institute-Deutsche Sammlung von Mikroorganismen und Zellkulturen, Braunschweig 38124, Germany.
Anika SteffenDepartment of Cell Biology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.ORCID 0000-0002-2933-0543
Christian SiebenDepartment of Nanoscale Infection Biology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.ORCID 0000-0002-2836-2623
Gang ZhaoDepartment of Systems Immunology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.
Jürgen TomaschDepartment of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.ORCID 0000-0002-3914-2781
Susanne HäusslerDepartment of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.ORCID 0000-0001-6141-9102

Funding

Deutsche Forschungsgemeinschaft (DFG) 390874280EC | European Research Council (ERC) 724290Novo Nordisk Fonden (NNF) 18OC0033946
6 · The paper itself

Abstract

Phenotypic diversification within pathogen populations can enhance survival in stressful environments, broaden niche colonization, and expand the ecological range of infectious diseases due to emerging collective pathogenicity characteristics. We describe a gene regulatory network property in the opportunistic pathogen

Indexed as

Epigenesis, GeneticHost-Pathogen InteractionsPseudomonas aeruginosaBacterial ProteinsEpigenetic MemoryGene Expression Regulation, BacterialGene Regulatory NetworksPhenotypePseudomonas InfectionsBacterial Proteinsepigenetic memoryGlpDglycerol metabolismPseudomonas aeruginosasingle-cell

Identifiers

PMID40591601
PMCPMC12260416

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.