Evidence map›Paper›PMID 40591402›Full record

ArticleHuman vaccines & immunotherapeutics2025

Global research trends in liver regeneration and immunomodulation: A perspective from bibliometric analysis.

Tongjie Xu, Dan Li

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tongjie XuDepartment of General Surgery (Hepatopancreatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Dan LiDepartment of Rehabilitation Medicine, Affiliated Hospital of Southwest Medical University, Luzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver regeneration is a complex process involving multiple cells, in which immunomodulation plays an important role in the process. However, there is lack of a comprehensive and objective summary of the current state of research and trends in the field. We retrieved articles on liver regeneration and immunomodulation published from 2004/01/01 to 2024/09/26, from the Web of Science Core Collection database. Authors, institutions, countries, journals and references were analyzed using bibliometric methods via CiteSpace and VOSviewer. A total of 4,992 articles were searched involving 102 countries or regions, 4,027 institutions and 26,830 authors. China is the country with the most articles in this field, and the United States ranks first in terms of citation/publication ratio (56.41). c-Met, liver regeneration, mesenchymal stem cells, extracellular matrix and angiogenesis are current research hotspots. While liver regeneration, targeted therapy, acute liver failure, hepatocellular carcinoma and mesenchymal stem cells are the themes and trends in this field. The study summarizes the research results in the field of immunomodulation and liver regeneration, and comprehensively analyses the research hotspots and trends, and provides an important basis for future applications and advances in the field.

Indexed as

BibliometricsBiomedical ResearchImmunomodulationLiver RegenerationAnimalsHumansbibliometricsimmunomodulationliver regenerationPartial hepatectomyresearch trends

Identifiers

PMID40591402
PMCPMC12218472

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.