Evidence map›Paper›PMID 40591395›Full record

RevieweLife2025

Current insights into insect immune memory.

Gabriela Krejčová, Adam Bajgar

Abstract readReview
In one paragraph

Review in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gabriela KrejčováDepartment of Molecular Biology and Genetics, Faculty of Science, University of South Bohemia, České Budějovice, Czech Republic.ORCID https://orcid.org/0000-0003-4648-973X
Adam BajgarDepartment of Molecular Biology and Genetics, Faculty of Science, University of South Bohemia, České Budějovice, Czech Republic.ORCID https://orcid.org/0000-0002-9721-7534

Funding

Grantová Agentura České Republiky 23-06133S
6 · The paper itself

Abstract

Traditionally, insects have been thought to be entirely dependent on their innate immune system, which has little capacity for the acquisition of experience from previous infections. However, much experimental evidence has challenged this view, showing that insects can develop long-term, pathogen-specific immune memory, which in some cases can be transmitted to offspring. Although significant progress has been made in this area, the underlying mechanism is still not fully understood, and a number of fundamental questions remain unanswered. In this review, we present an overview of documented cases of insect immune memory and summarize the experimental evidence in support of the prevailing hypotheses on the mechanism of antiviral and antibacterial immune memory in insects. We also highlight key questions that remain unanswered and discuss

Indexed as

Drosophila melanogasterImmunity, InnateImmunologic MemoryInsectaAnimalsDscamevolutionary biologyhemocytesimmune memoryimmunologyinflammationinsect immunityinsect vaccinationtrained immunity

Identifiers

PMID40591395
PMCPMC12212918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.