ArticleJournal of ophthalmic inflammation and infection2025
Clinical findings, outcomes following management and complications of acute retinal necrosis: the experience of a tertiary eye centre in Saudi Arabia.
Article in Journal of ophthalmic inflammation and infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- CMV retinitis: the diagnostic challenges and long-term outcomes. The experience of tertiary eye center in Saudi Arabia.Journal of ophthalmic inflammation and infection · 2026Article
- Acute Retinal Necrosis with Choroidal Inflammation, Optic Perineuritis, and Early Retinal Detachment: A Case Report.Case reports in ophthalmologyArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo study the clinical picture, outcomes and the complications of acute retinal necrosis (ARN) in a tertiary eye hospital.
methodsThis is retrospective chart review of all patients who were diagnosed with ARN and were treated and followed up at King Khaled Eye Specialist Hospital (KKESH). Details of clinical examinations, Polymerase Chain Reaction (PCR) results, systemic and topical treatments, complications and managements of complications were obtained.
resultsTwenty eight eyes of 26 patients were included. The results of PCR were positive in 22 eyes. Systemic antiviral therapy with intravenous Acyclovir 10 mg/Kg three times daily was given to all cases. Eight patients were treated with intravitreal ganciclovir injections. Fifteen eyes (56.3%) had rhegmatogenous retinal detachment (RRD) and 11 of them had surgical interventions. The risk of developing RRD was significantly high in severe vitritis (P = 0.007, OR = 3.825), diffuse or multifocal retinitis (P = 0.010, OR = 1.04) and the larger extent of retinitis (P = 0.016). The final visual outcome was worse among eyes which developed RRD (LogMAR 1.6 ± 0.94, Snellen = 20/800) than eyes which did not develop RRD (LogMAR 0.81 ± 0.84, Snellen = 20/125) and the difference was statistically significant (P = 0.031).
conclusionThe visual outcomes of ARN are significantly worse in eyes which develop RRD. More severe and larger extent of posterior segment involvement confer higher risks of RRD development in ARN.
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