Evidence map›Paper›PMID 40591181›Full record

ReviewDiscover oncology2025

Systematic review of transarterial chemoembolization for desmoid tumors: a promising locoregional treatment for challenging tumor.

Abdulrahman Alaseem, Naif Alsaikhan, Abdulaziz M AlSudairi, Yazeed A Alsehibani, Mohammed N Alhuqbani, Zyad A Aldosari, Omar A Aldosari, Abdulaziz Almuhanna, Ibrahim S Alshaygy

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abdulrahman AlaseemDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia. abalaseem@ksu.edu.sa.
Naif AlsaikhanDepartment of Radiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Abdulaziz M AlSudairiDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Yazeed A AlsehibaniDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Mohammed N AlhuqbaniDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Zyad A AldosariDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Omar A AldosariDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Abdulaziz AlmuhannaOrthopedic Surgery Department, King Saud Medical City, Riyadh, Saudi Arabia.
Ibrahim S AlshaygyDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDesmoid tumors are rare, locally invasive nonmetastatic tumors that arise from soft tissues. Due to the complexity of desmoid tumor therapy, each patient's particular needs and preferences must be considered in a multidisciplinary strategy. To provide innovative therapeutic approaches and improve the results for patients with desmoid tumors, ongoing research, and collaboration within the medical community are essential. SEARCH

methodsA comprehensive search of three databases was conducted from inception to June 2024 to identify all relevant cases of chemoembolization for desmoid tumors. Data from these cases were systematically extracted and analyzed to assess the procedure's overall efficacy and safety concerns. SEARCH

resultsA total of 6 studies were identified in the literature with a combined sample size of 43 patients. Doxorubicin was the predominant chemotherapeutic agent administered using drug-eluting microbeads (DEB-TACE). The magnitude of size reduction varied from 21 to 97%. Most studies observed a decrease in size exceeding 50%. All 43 patients observed a decrease in symptoms following the procedures.

conclusionsThis review emphasizes that chemoembolization shows potential as a reliable and low-risk approach for treating desmoid tumors. Chemoembolization can be used especially when the tumors are large or located in anatomically complex areas with clearly defined blood vessels.

Indexed as

ChemoembolizationDesmoidInterventional radiologyOncologySoft tissue tumors

Identifiers

PMID40591181
PMCPMC12214221

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.