Evidence map›Paper›PMID 40591140›Full record

ArticleDiscover oncology2025

Rosmarinus officinalis suppresses cancer cell viability and inflammatory mediators in RAW 264.7 cells: in vitro and in silico analysis.

Hamza Assaggaf, Naoufal El Hachlafi, Nidal Naceiri Mrabti, Mohamed Taibi, Amine Elbouzidi, Ahmed Qasem, Ammar Attar, Fahad M Alshabrmi, Long Chiau Ming, Said Moshawih and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hamza AssaggafClinical Laboratory Sciences Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, 21955, Saudi Arabia.
Naoufal El HachlafiFaculty of Medicine and Pharmacy, Ibn Zohr University, 81000, Guelmim, Morocco.
Nidal Naceiri MrabtiFaculty of Sciences Dhar El Mehraz, Sidi Mohamed Ben Abdellah University, 30 000, Fez, Morocco.
Mohamed TaibiLaboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences, Université Mohammed Premier, 60000, Oujda, Morocco.
Amine ElbouzidiLaboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences, Université Mohammed Premier, 60000, Oujda, Morocco.
Ahmed QasemClinical Laboratory Sciences Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, 21955, Saudi Arabia.
Ammar AttarClinical Laboratory Sciences Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, 21955, Saudi Arabia.
Fahad M AlshabrmiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, 51452, Saudi Arabia.
Long Chiau MingDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia.
Said MoshawihDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan.
Chrismawan ArdiantoDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia. chrismawan.ff@gmail.com.
Hanae Naceiri MrabtiHigh Institute of Nursing Professions and Health Techniques Casablanca, 20250, Casablanca, Morocco.
Abdelhakim BouyahyaLaboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, Mohammed V University in Rabat, 10100, Rabat, Morocco. a.bouyahya@um5r.ac.ma.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Called widely as rosemary, Rosmarinus officinalis is a fragrant herb that has been used for centuries for its medicinal properties and wide range of bioactive components. In order to better understand the anti-inflammatory and anticancer effects of R. officinalis essential oil (ROEO), this study will examine it. The gas chromatography-mass spectrometry (GC-MS) examinations revealed that 1,8-cineole (37.24%) was the main constituent in ROEO, followed by α-pinene (18.43%) and camphor (13.04%). In addition, while maintaining the survival of normal cells, ROEO demonstrated notable cytotoxic effect on MCF-7 (IC

Indexed as

Breast cancerCancerDensity functional theory (DFT)Human and illnessMolecular dockingRAW 264.7 murine macrophages

Identifiers

PMID40591140
PMCPMC12214115

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.