Evidence map›Paper›PMID 40590960›Full record

ArticlePediatric surgery international2025

Outcome analysis of surgical complications in pediatric solid tumors: a retrospective clinical study.

Arihant Jain, Nitin James Peters, Ram Samujh, Amita Trehan, Muneer Abas Malik, Renu Madan, Shivani Dogra, Shailesh Solanki, Jitender Singh, Ravi P Kanojia and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Arihant JainDepartment of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Nitin James PetersDepartment of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India. nitinjamespeters@yahoo.com.
Ram SamujhDepartment of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Amita TrehanDepartment of Pediatrics, Pediatric Haematology, and Oncology Division, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Muneer Abas MalikDepartment of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Renu MadanDepartment of Radiation Oncology and Regional Cancer Center, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Shivani DograDepartment of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Shailesh SolankiDepartment of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Jitender SinghDepartment of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Ravi P KanojiaDepartment of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Deepak BansalDepartment of Pediatrics, Pediatric Haematology, and Oncology Division, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Richa JainDepartment of Pediatrics, Pediatric Haematology, and Oncology Division, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Monika BawaDepartment of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Rakesh KapoorDepartment of Radiotherapy, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Sandhya YaddanapudiDepartment of Anesthesia, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
J K MahajanDepartment of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostoperative complications can significantly impact patient outcomes and quality of life, particularly in children with solid tumors. These complications may delay the commencement of adjuvant therapy. This study aimed to evaluate the severity and effects of these complications and to validate the Clavien-Dindo classification system in pediatric patients following surgery for solid tumors.

methodsA retrospective analysis was conducted on postoperative complications in children with solid tumors at a tertiary care teaching hospital over 5 years. Patient demographics and tumor types were recorded, and complications were categorized using the Clavien-Dindo classification. The study identified key risk factors for complications and their implications for patient care.

resultsWe included 188 patients, out of which the majority (n = 157; 83.5%) had low-grade (grade 1 or 2) postoperative complications. Higher intraoperative blood loss (p < 0.001), adjacent organ infiltration, and longer operative times were associated with more severe grade of complications. Patients with higher-grade complications also had longer hospital stays (Kendall's Tau coefficient of 0.48). Among the 26 patients with tumor recurrence, 30% had experienced severe complications (grades 3 and 4). The Kaplan‒Meier curve and log-rank test (p < 0.001) showed that severe complications are linked to a lower survival probability.

conclusionsThe analysis of complications showed a significant effect on short-term surgical outcomes, and severe complications may also impact oncological outcomes. The Clavien-Dindo classification is a useful tool for grading postoperative complications in pediatric surgical oncology. LEVEL OF EVIDENCE: Level III.

Indexed as

NeoplasmsPostoperative ComplicationsAdolescentChildChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesRisk FactorsTreatment OutcomeAdjuvant therapyClavien–Dindo classificationInterleukin-6Pediatric solid tumorsPostoperative complicationsQuality improvement

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.