Evidence map›Paper›PMID 40590949›Full record

ArticlePediatric radiology2025

Treatment outcome of ultrasound-guided hydrostatic reduction of intussusception and its associated factors among pediatric patients in a resource-limited setting.

Chala Takele Ayana, Tesfahunegn Feleke, Anduamlak Bazezew, Zelalem Mehari, Yodit Abraham Yaynishet, Tewodros Getinet, Merga Belina, Samuel Sisay Hailu

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Article in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

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3citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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3 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chala Takele AyanaBahir Dar University, Bahir Dar, Ethiopia.
Tesfahunegn FelekeAddis Ababa University, Addis Ababa, Ethiopia. tesfa.feleke21@aau.edu.et.
Anduamlak BazezewBahir Dar University, Bahir Dar, Ethiopia.
Zelalem MehariBahir Dar University, Bahir Dar, Ethiopia.
Yodit Abraham YaynishetAddis Ababa University, Addis Ababa, Ethiopia.
Tewodros GetinetSt. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Merga BelinaAddis Ababa University, Addis Ababa, Ethiopia.
Samuel Sisay HailuChildren's Hospital of Philadelphia, Philadelphia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUltrasound (US)-guided hydrostatic reduction of intussusception was recently introduced and adopted as the first-line management for intussusception in children at Tibebe Ghion Specialized Hospital. Knowledge of the treatment outcome and associated factors will enhance the expansion of this technique to hospitals in Sub-Saharan Africa, where surgery largely remains the exclusive treatment strategy.

methodsAn institution-based cross-sectional study was conducted at Tibebe Ghion Specialized Hospital, Bahir Dar, Ethiopia. We consecutively enrolled children with US-confirmed intussusception for whom US-guided hydrostatic reduction with normal saline was performed by a general radiologist and/or final-year residents under supervision after ruling out contraindications. Firth's logistic regression analysis was undertaken to determine odds ratios (ORs) and 95% confidence intervals (CIs) of factors predictive of successful outcomes.

resultsA total of 145 children with a mean age of 24 months were enrolled in the current study. Most patients (123, 84.8%) presented within 24 h of symptom onset, with colicky abdominal pain being the main complaint (79, 54.5%). Ileocolic type and short-length intussusception were visualized more on US, 135 (93.1) and 118 (81.4%), respectively. The overall reduction rate was 93.1% (95% CI [89.0-97.2]). Ten patients (6.9%) underwent surgery after a failed hydrostatic reduction, with good postoperative outcomes. Reported duration of illness of less than 24 h, adjusted odds ratio (AOR) of 6.77 (95% CI [1.25-30.42]), and length of intussusception of less than 3 cm (AOR, 6.24; 95% CI [1.18-33.00]) were significantly associated with successful hydrostatic reduction outcomes.

conclusionWe have found a high US-guided hydrostatic reduction rate of intussusception in an implementation phase and a relatively low resource setup. Early presentation and short intussusception segment were favorably associated with successful outcomes.

Indexed as

Abdominal PainHydrostatic PressureIntussusceptionResource-Limited SettingsAdolescentChildChild, PreschoolContraindications, ProcedureCross-Sectional StudiesDeveloping CountriesEthiopiaFemaleHumansInfantMaleTreatment OutcomeEthiopiaHydrostatic reductionIntussusceptionPediatric emergencyPediatric radiologyUltrasonography

Identifiers

PMID40590949

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.