Evidence map›Paper›PMID 40590922›Full record

ArticleAnalytical and bioanalytical chemistry2025

Strychnos peckii B.L. Rob.: secondary metabolite annotation by liquid chromatography tandem high-resolution mass spectrometry with insights from biogenesis.

Fernando Cassas, Carla L G Santos, Felipe M A da Silva, Quezia B Cass

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Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Fernando CassasSeparare - Núcleo de Pesquisa em Cromatografia, Departamento de Química, Universidade Federal de São Carlos, (UFSCAR), São Carlos, SP, Brazil.
Carla L G SantosCentro de Apoio Multidisciplinar, Universidade Federal Do Amazonas (UFAM), Manaus, AM, Brazil.
Felipe M A da SilvaCentro de Apoio Multidisciplinar, Universidade Federal Do Amazonas (UFAM), Manaus, AM, Brazil.
Quezia B CassSeparare - Núcleo de Pesquisa em Cromatografia, Departamento de Química, Universidade Federal de São Carlos, (UFSCAR), São Carlos, SP, Brazil. qcass@ufscar.br.ORCID http://orcid.org/0000-0002-6550-1194

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 172986/2023-0Conselho Nacional de Desenvolvimento Científico e Tecnológico 302464/2022-0Conselho Nacional de Desenvolvimento Científico e Tecnológico 315040/2021-1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2014/50244-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/15815-1
6 · The paper itself

Abstract

Alkaloids from the Strychnos genus exhibit remarkable chemical diversity and are considered promising candidates for drug development. However, many endemic species remain unexplored. In this study, we report the use of a scouting liquid chromatographic system for method development and a liquid chromatography system hyphenated to high-resolution mass spectrometry (LC-HRMS) to efficiently profile and annotate the specialized metabolites of Strychnos peckii B.L. Rob. A structural database was employed to curate the data through MS

Indexed as

AlkaloidsStrychnosTandem Mass SpectrometryChromatography, High Pressure LiquidChromatography, LiquidSecondary MetabolismAlkaloidsBiogenesisOrthogonal columnsSpecialized metabolitesStrictosidine derivatesβ-carboline alkaloids

Identifiers

PMID40590922

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.