Evidence map›Paper›PMID 40590905›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Lysosome-escaping and nucleus-targeting nanomedicine for enhanced cancer catalytic internal radiotherapy.

Weiwei Su, Han Wang, Shuai Zhao, Xiuru Ji, Hongjing Jiang, Kexian Li, Changjing Zuo, Jianming Zheng, Dalong Ni, Jiajia Hu

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Weiwei SuDepartment of Radiology, Naval Medical Center, Shanghai, China.
Han WangDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shuai ZhaoDepartment of Nuclear Medicine, Changhai Hospital, Naval Medical University (Second Military Medical University), Shanghai, China.
Xiuru JiDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hongjing JiangDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Kexian LiResearch Department, Naval Medical Center, Shanghai, China.
Changjing ZuoDepartment of Nuclear Medicine, Changhai Hospital, Naval Medical University (Second Military Medical University), Shanghai, China. cjzuo@smmu.edu.cn.
Jianming ZhengDepartment of Pathology, Changhai Hospital, Naval Medical University (Second Military Medical University), Shanghai, China. jmzheng1962@163.com.
Dalong NiDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ndl12353@rjh.com.cn.ORCID 0000-0001-6679-5414
Jiajia HuDepartment of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Er Road, Huang Pu District, Shanghai, 200025, China. jiajiahu@shsmu.edu.cn.

Funding

National Funding Post-doctoral Researcher Program GZC20233556National Natural Science Foundation of China 82103034National Natural Science Foundation of China 82171976National Natural Science Foundation of China 82272040National Natural Science Foundation of China 92359204Shanghai Pujiang Program 21PJD042Shanghai Sailing program 23YF1440200
6 · The paper itself

Abstract

purposeRadio-nanomedicine, such as

methodsTiO

resultsThe labelling rates of

conclusion

Indexed as

Cell NucleusLysosomesNanomedicinePancreatic NeoplasmsAnimalsApoptosisCatalysisCell Line, TumorHumansIodine RadioisotopesMiceReactive Oxygen SpeciesTitaniumIodine-125Iodine RadioisotopesReactive Oxygen SpeciesTitaniumtitanium dioxideLysosome escapingNucleus targetingRadio-nanomedicineTAT/HA2Tumour treatment

Identifiers

PMID40590905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.